[The monosodium salt of montelukast, a selective and orally active leukotriene receptor antagonist with anti-inflammatory and bronchodilator activity. Montelukast sodium selectively and competitively blocks the cysteinyl leukotriene 1 (CysLT1) receptor, thereby preventing leukotriene D4 from binding to its receptor. This prevents leukotriene-mediated activities, including enhanced migration of eosinophils and neutrophils, increased adhesion of leukocytes, increased monocyte and neutrophil aggregation, increased airway edema, increased capillary permeability and bronchoconstriction. ( NCI )]
UMLS (NCI) C0380447 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: MONTELUKAST
Relation/CHD: MONTELUKAST SODIUM 10 MG
MONTELUKAST SODIUM 5 MG
MONTELUKAST SODIUM 4 MG