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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RE RE- REA REB REC RED REE REF REG REH REI REJ REL REM REN REO REP REQ RER RES RET REU REV REW REX

RET/D10S170 Oncogene

[The PTC1 chimeric oncogene (RET/PTC1, RET/H4) is generated by fusion of the RET proto-oncogene receptor tyrosine kinase domain to the 5-prime terminal region of the H4 gene containing a putative leucine zipper. H4 shows no significant homology to known genes and the protein function is unknown. The RET receptor ligand is Glial Cell Line-Derived Neurotrophic Factor. The putative H4 leucine zipper mediates dimerization of the PTC1 oncoprotein, essential for PTC1 transforming activity. (NCI) ( NCI )]
UMLS (NCI) C0919512
RET/H4 Oncogene
RET/PTC1 Oncogene
Transforming Sequence, Thyroid 1
TST1 Oncogene
 
Gene or Genome

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