[Encoded by human RGS2 Gene (RGS Family), 211-aa 24-kDa Regulator of G-Protein Signaling 2 is a basic HLH phosphoprotein containing 1 RGS domain with similarity to lymphocyte-specific 1R20 and phosphorylated by PKC. RGS2 inhibits signal transduction by increasing GTPase activity of G protein alpha subunits, driving them into the inactive GDP-bound form. RGS2 also reduces cAMP production by inhibiting odorant-stimulated Alpha-OLF linked adenylyl cyclase type III activity in olfactory neurons. (NCI) ( NCI )]
UMLS (NCI) C0254619 - Amino Acid, Peptide, or Protein
- Biologically Active Substance