[Encoded by human RGS3 Gene (RGS Family), 519-aa 56.6-kDa cytosolic Regulator of G-Protein Signaling 3 contains 1 RGS domain and is likely phosphorylated by cyclic GMP-dependent protein kinase. RGS3 inhibits G-protein mediated signal transduction by increasing G protein alpha subunit GTPase activity, promoting its conversion to the inactive GDP-bound form. G-protein activation leads to translocation of RGS3 to the plasma membrane. (NCI) ( NCI )]
UMLS (NCI) C1450151RGS3
- Amino Acid, Peptide, or Protein
- Biologically Active Substance