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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RE RE- REA REB REC RED REE REF REG REH REI REJ REL REM REN REO REP REQ RER RES RET REU REV REW REX

Retinoic Acid Receptor RXR-Gamma

[Encoded by human RXRG Gene (NR2/RXR Family), 463-aa 51-kDa nuclear Retinoid X Receptor Gamma is a transcriptional regulator composed of N-terminal modulating domain, DNA-binding domain, and C-terminal 9-cis RA-binding domain. Involved in the retinoic acid response pathway, RXRG acts as heterodimeric partner for RARA, RARB, RARG, TH-, and vitamin D receptor and mediates RA biological effects by binding specific target gene promoter sequences and inducing activation of target gene transcription. RARB/RXRB and RARB/RXRG may regulate locomotion and be functionally redundant. RXR/LXRs and RXR/FXR may mediate cholesterol homeostasis, by governing cholesterol transport from peripheral cells, inhibiting cholesterol absorption in the small intestine, and repressing bile acid synthesis through upregulation of ABC1 and repression of CYP7A1 expression. (NCI) ( NCI )]
UMLS (NCI) C0527032
 
Amino Acid, Peptide, or Protein
Receptor

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