- 1. TEL-AML1
- [Fusion protein containing the helix-loop-helix domain of TEL, a member of the ETS-like family of transcription factors, and the DNA-binding and transactivation domains of the transcription factor AML1. Encoded by the TEL-AML1 gene, which arises from a chromosomal translocation. ( NCI )] (UMLS (NCI) C0531832) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 28. TELERADIO USING PHOTONS
- (UMLS (ICD9CM) C0203549) =Therapeutic or Preventive Procedure
|
- 2. TEL/AML1 Chimeric Gene
- [The result of a t(12;21) translocation, TEL-AML1 Oncogene encodes a fusion protein containing the helix-loop-helix domain of TEL, a member of the ETS-like family of transcription factors, and the DNA-binding and transactivation domains of the transcription factor AML1. (NCI) ( NCI )] (UMLS (NCI) C0919449) TEL/AML1 Fusion Gene;
TEL-AML1 Oncogene;
=Gene or Genome ;
| - 29. Teleradiology
- [The electronic transmission of radiological images from one location to another for the purposes of interpretation and/or consultation. Users in different locations may simultaneously view images with greater access to secondary consultations and improved continuing education. (From American College of Radiology, ACR Standard for Teleradiology, 1994, p3) ( NCI )] (UMLS (NCI) C0162647) =Health Care Activity ;
|
- 3. tela choroidea
- [ ] (UMLS (CSP) C0598169) =Body Part, Organ, or Organ Component
| - 30. Teletypewriter
- (UMLS (HL7) C1549673) =Manufactured Object =Telecommunication equipment type;
|
- 4. telangiectasia
- [localized convolution and dilatation of a group of small blood vessels, leading to hemorrhage and angioma. ( CSP )] (UMLS (NCI) C0039446) =Disease or Syndrome ;
=blood vessel disorder;
=ataxia telangiectasia;
HEREDIT HEMORR TELANGIEC;
CREST syndrome;
| - 31. television
- [The transmission and reproduction of transient images of fixed or moving objects. An electronic system of transmitting such images together with sound over a wire or through space by apparatus that converts light and sound into electrical waves and reconverts them into visible light rays and audible sound. (From Webster, 3rd ed) ( MSH )] (UMLS (CSP) C0039461) =Manufactured Object ;
=mass information media;
|
- 5. Telangiectatic Glomangioma
- [A glomus tumor characterized by huge vascular channel formations. ( NCI )] (UMLS (NCI) C1336699) =Neoplastic Process ;
| - 32. Telida Village
- (UMLS (HL7) C1551001) =Population Group =NativeEntityAlaska;
|
- 6. TELBIVUDINE
- (UMLS (NCI) C1453933) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 33. TELITHROMYCIN
- (UMLS (NCI) C0907410) =Organic Chemical; Antibiotic ;
|
- 7. telecare
- [ ] (UMLS (CSP) C0872369) =Health Care Activity ;
| - 34. Telnet
- [Reference to interactive sessions [RFC 1738]. Some sites, (e.g., laboratories) have TTY based remote query sessions that can be accessed through telnet. http://www.ietf.org/rfc/rfc1738.txt ( HL7V3.0 )] (UMLS (HL7) C1555019) =Idea or Concept =URLScheme;
|
- 8. telecommunication
- [transmission of information over distances via electronic means. ( CSP )] (UMLS (CSP) C0039449) =Machine Activity ;
=communication;
informatics | - 35. TELOGEN EFFLUVIUM
- [ ] (UMLS (ICD9CM) C0263518) =Disease or Syndrome
|
- 9. Telecommunication Address
- (UMLS (HL7) C1552673) =Idea or Concept =Universal Resource Locator;
| - 36. telomerase
- [nonEC; reverse transcriptase like ribonucleoprotein that maintains the telomere sequence; expressed in tumor cells but not in normal cells. ( CSP )] (UMLS (CSP) C0087071) =Amino Acid, Peptide, or Protein; Enzyme ;
=EC 2.7.7;
|
- 10. Telecommunication equipment type
- (UMLS (HL7) C1547612) =Manufactured Object =HL7 Vocabulary Version 2.5;
=dataphone;
Phone;
fax;
Beeper;
Telecommunications Device for the Deaf;
Cell;
Internet Address: Use Only If Telecommunication Use Code Is NET;
Teletypewriter;
X.400 email address: Use Only If Telecommunication Use Code Is NET | - 37. Telomerase Protein Component 1
- [Telomerase-associated protein, TEP1, the non-catalytic subunit of telomerase, appears to bind to telomerase RNA, the RNA template required for telomere repeat synthesis. In addition to TEP1, telomerase contains the RNA component, TERC, and an enzymatic component, TERT. TEP1, the homologue of the Tetrahymena p80 telomerase protein, is widely expressed. It is also a component of Vault, a large cytoplasmic ribonucleoprotein of undetermined function. (from OMIM 601686 and NCI) ( NCI )] (UMLS (NCI) C0535752) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 11. Telecommunication use code
- (UMLS (HL7) C1547611) =Intellectual Product =HL7 Vocabulary Version 2.5;
=Answering Service Number;
Beeper Number;
Emergency Number;
Network (email) Address;
Other Residence Number;
Primary Residence Number;
Vacation Home Number;
Work Number;
| - 38. Telomerase Reverse Transcriptase Gene
- [This gene is involved in cell cycle regulation and telomere maintenance. ( NCI )] (UMLS (NCI) C1367342) TERT;
TERT Gene =Gene or Genome |
- 12. TelecommunicationAddressUse
- (UMLS (HL7) C1553731) =Intellectual Product =CodeSystem;
=answering service;
pager;
mobile contact;
Emergency contact | - 39. Telomerase Reverse Transcriptase Protein
- [Telomerase reverse transcriptase protein, TERT, adds telomeric DNA to the ends of eukaryotic chromosomes. Telomerase contains three subunits: the catalytic subunit TERT, an RNA component TERC, and a non-catalytic protein TEP1. Telomerase preserves chromosome integrity by maintaining telomere length; small amounts of sequence are lost because of incomplete DNA replication. Telomerase adds telomeric repeats to the 3-prime end of a G-rich primer using an RNA template. This enzyme activity is undetectable in most normal cells, but present in immortal cells and cancer tissues. Telomerase activity is an independent prognostic factor in neuroblastoma. MYC, the ubiquitous transcription factor that controls cell proliferation, directly activates transcriptional expression of TERT. (from J Clin Oncol 2000. 18:2582, OMIM 187270 and NCI) ( NCI )] (UMLS (NCI) C0754515) Telomere Reverse Transcriptase;
TERT =Amino Acid, Peptide, or Protein; Enzyme |
- 13. Telecommunications Device for the Deaf
- (UMLS (HL7) C0183841) =Manufactured Object =Telecommunication equipment type;
| - 40. Telomerase RNA Component Gene
- [This gene plays a role in chromosomal repair and telomere maintenance. ( NCI )] (UMLS (NCI) C1366448) TERC;
TERC Gene =Gene or Genome |
- 14. telefax
- [Participation by text or diagrams printed on paper that have been transmitted over a fax device ( HL7V3.0 )] (UMLS (HL7) C1553518) =Idea or Concept =written;
| - 41. Telomerase-Associated Protein 1 Gene
- [This gene plays a role in telomerase activity. ( NCI )] (UMLS (NCI) C1336603) TEP1;
TEP1 Gene =Gene or Genome ;
|
- 15. telehealth
- [Describes health care provided to remote patients using a combination of satellite dishes, computers, and video-conferencing equipment. (Wordspy.com) ( NCI )] (UMLS (CSP) C1328956) =Health Care Activity ;
| - 42. Telomerase: 540-548 Peptide Vaccine
- [A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells. (NCI04) ( NCI )] (UMLS (NCI) C0935896) Telomerase:540-548 Peptide;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 16. telemedicine
- [delivery of health services via remote telecommunications; includes interactive consultative and diagnostic services. ( CSP )] (UMLS (CSP) C0162648) =Health Care Activity ;
=biomedical automation;
| - 43. Telomere
- [specialized DNA-protein structures found at the ends of eukaryotic chromosomes with the function of stabilizing chromosomes; telomerase is the RNA-dependent DNA polymerase responsible for the synthesis of telomere DNA. ( CSP )] (UMLS (NCI) C0085187) =Cell Component ;
=Chromosomal;
|
- 17. telemetering
- [ ] (UMLS (CSP) C0599520) =Diagnostic Procedure ;
| - 44. Telomere Capping
- [Telomere capping protects chromosome ends from cellular DNA-damage responses, such as cell cycle arrest or apoptosis. Telomere capping involves multiple molecular pathways and at least four distinct structural components contribute to telomere capping: (1) the higher order telomeric DNA-protein complex, whose overall length (i.e., the number of telomeric repeats) dictates whether telomerase or nuclease can access telomeric DNA; (2) the protein complex found on the terminal few repeats; (3) the DNA-protein complex on the single stranded G-rich DNA extension of the telomere, which is most likely important for preventing DNA damage response and regulating the cell cycle dependent structure of the telomere; and (4) telomerase itself. Telomere capping is influenced by multiple, mutually reinforcing factors including telomere length, although telomere length is only one of several determinants of telomere functionality. (from PMID 11850780 and NCI) ( NCI )] (UMLS (NCI) C1155302) =Genetic Function
|
- 18. telemetry
- [measurements made at a distance from the subject which are transmitted by radio signals. ( CSP )] (UMLS (CSP) C0039451) =Diagnostic Procedure ;
=Monitor;
| - 45. Telomere Maintenance
- [Telomeres enable cells to distinguish natural chromosome ends from damaged DNA because uncapped telomeres elicit a DNA damage response that halts cell proliferation. The protection of human chromosome ends primarily depends on the telomeric protein TRF2 and telomere capping involves the formation of a higher order structure, the telomeric loop or t-loop. Telomeres consist of a tandem array of telomeric DNA repeats bound to specialized telomeric proteins. Telomerase activity lengthens terminal regions of eukaryotic telomeric DNA by RNA-templated addition of repeated DNA sequences. Active telomerase forms a structure at the telomere that prevents chromosome ends from being sensed as DNA damage. Telomerase is regulated by sequence-specific DNA binding proteins that bind telomeric DNA repeats. Through separate domains, these proteins bind additional proteins to assemble a higher-order complex on the telomeric DNA. (from PMID 11850778 and NCI) ( NCI )] (UMLS (NCI) C1155299) =Genetic Function
|
- 19. telencephalic leukoencephalopathy
- [condition in which there is a deviation from or interruption of the normal structure or function of the white matter of the telencephalon, occurring most frequently in infants and children. ( CSP )] (UMLS (CSP) C0597559) =Disease or Syndrome ;
=encephalitis;
myelinopathy | - 46. Telomere Maintenance Gene
- [Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a damage response that halts cell proliferation. Telomerase, which lengthens telomeric DNA by RNA-templated addition of repeated DNA sequences, is regulated by proteins that bind to the telomeric DNA repeats and to additional proteins to assemble a higher-order telomeric complex. (NCI) ( NCI )] (UMLS (NCI) C1336700) =Gene or Genome ;
|
- 20. telencephalon
- [paired cerebral vesicles, which are the anterolateral evaginations of the prosencephalon, together with the median, unpaired portion, the lamina terminalis; from it the cerebral hemispheres are derived. ( CSP )] (UMLS (CSP) C0039452) =Body Part, Organ, or Organ Component ;
=forebrain;
=basal ganglia;
corpus callosum;
cerebrum;
| - 47. Telomeric Repeat Binding Factor (NIMA-Interacting) 1
- [This protein is a telomere specific binding protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. (from LocusLink) ( NCI )] (UMLS (NCI) C1504634) Telomeric Repeat Binding Factor 1;
Telomeric-Repeat Binding Factor 1;
TERF1;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 21. telenursing
- [ ] (UMLS (CSP) C0872283) =Health Care Activity ;
| - 48. Telomeric Repeat Binding Factor (NIMA-Interacting) 1 Gene
- [This gene plays a role in telomere length maintenance and the inhibition of telomerase activity. ( NCI )] (UMLS (NCI) C1336604) TERF1;
TERF1 Gene =Gene or Genome ;
|
- 22. teleost
- [ ] (UMLS (CSP) C0599050) =Fish
| - 49. Telomeric Repeat Binding Factor 2
- [This protein is a telomere specific binding protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. (LocusLink) ( NCI )] (UMLS (NCI) C1336702) Telomeric-Repeat Binding Factor 2;
TERF2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 23. Telephone
- (UMLS (HL7) C1576872) =Idea or Concept =Consent Mode;
| - 50. Telomeric Repeat Binding Factor 2 Gene
- [This gene is involved in the negative regulation of telomerase activity. ( NCI )] (UMLS (NCI) C1336605) TERF2;
TERF2 Gene =Gene or Genome ;
|
- 24. telephone
- [Participation by voice communication where the voices of the communicating parties are transported over an electronic medium ( HL7V3.0 )] (UMLS (HL7) C1548940) =Idea or Concept =verbal;
| - 51. Telomeric-Repeat Binding Factor
- [Human telomeric-repeat binding factor proteins (TRF) 1 and 2 are involved in the control of telomere dynamics in vivo. Reduced expression of TRF1 and TRF2 mRNAs was observed in human malignant hematopoietic and acute leukemia cell lines. However, expression of TRF1 and TRF2 mRNAs increased during differentiation of malignant hematopoietic cell line when induced artificially. Furthermore, studies from gastrointestinal carcinogenesis suggested that down-regulation of the TRF1 expression in tumor cells may be involved in cell immortalization. Together with hTERT, TRF1 and TRF2 are important regulators of telomerase activity and represent potential targets for cancer therapy. ( NCI )] (UMLS (NCI) C1336701) TRF Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 25. Telephone
- [A voice telephone number [http://www.ietf.org/rfc/rfc3966.txt and http://www.ietf.org/rfc/rfc2806.txt]. ( HL7V3.0 )] (UMLS (HL7) C1576871) =Idea or Concept =URLScheme;
| - 52. telophase
- [The final phase of cell nucleus division following ANAPHASE, in which two daughter nuclei are formed, the CYTOPLASM completes division, and the CHROMOSOMES lose their distinctness and are transformed into CHROMATIN threads. ( MSH )] (UMLS (CSP) C0039465) =Temporal Concept ;
|
- 26. Telephone number
- (UMLS (HL7) C1547404) =Idea or Concept =Data type;
| - 53. Teludipine Hydrochloride
- (UMLS (NCI) C0292595) =Organic Chemical; Pharmacologic Substance
|
- 27. Telephone Number
- (UMLS (HL7) C1548319) =Idea or Concept =Value type;
| |
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