- 701. BENZPHETAMINE
- [A sympathomimetic agent with properties similar to DEXTROAMPHETAMINE. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222) ( MSH )] (UMLS (NCI) C0005096) =Organic Chemical; Pharmacologic Substance
| - 751. beta caveolin
- [ ] (UMLS (CSP) C0287873) =Amino Acid, Peptide, or Protein; Receptor
|
- 702. Benzphetamine Hydrochloride
- (UMLS (NCI) C0546851) =Organic Chemical; Pharmacologic Substance =BENZPHETAMINE;
=BENZPHETAMINE HYDROCHLORIDE 50 MG;
BENZPHETAMINE HYDROCHLORIDE 25 MG | - 752. Beta Cell
- [A cell that composes the bulk of the islets of Langerhans and secretes insulin. ( NCI )] (UMLS (NCI) C0030281) =Cell ;
|
- 703. benzpyrinium
- [ ] (UMLS (CSP) C0599261) =Organic Chemical; Pharmacologic Substance
| - 753. Beta Cell Neoplasm
- [A usually benign, well circumscribed neoplasm arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin. ( NCI )] (UMLS (NCI) C0021670) =Neoplastic Process =Islet Cell Adenoma;
|
- 704. BENZQUINAMIDE
- (UMLS (NCI) C0053284) =Organic Chemical; Pharmacologic Substance ;
=[GA700] ANTIEMETICS;
quinolizine =BENZQUINAMIDE HYDROCHLORIDE;
| - 754. Beta Cellulin
- [Betacellulin is a member of the EGF family of growth factors; a potent mitogen for retinal pigment epithelia and vascular smooth muscle cells. Betacellulin effects may be mediated by the EGF receptor and/or related receptors. The precursor form is a type I membrane protein that contains one EGF-like domain and is synthesized in several tissues and tumor cells. Betacellulin from pancreatic beta cells could play a role in the vascular complications associated with diabetes. (from Swiss-Prot P35070 and NCI) ( NCI )] (UMLS (NCI) C0213553) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 705. benztropine
- [centrally active muscarinic antagonist that has been used in the symptomatic treatment of Parkinson disease; also inhibits the uptake of dopamine. ( CSP )] (UMLS (CSP) C0005098) =Organic Chemical; Pharmacologic Substance
| - 755. Beta Chemokine
- [Encoded by CC Cytokine Genes, Beta Chemokines are CC-type dual-cysteine chemokines with adjacent cysteine residues in their primary sequence that act as chemoattractants for lymphocytes, monocytes, eosinophils, and basophils, but not for neutrophils. (NCI) ( NCI )] (UMLS (NCI) C0282552) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 706. Benzydamine Hydrochloride
- [An indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride does not inhibit cyclooxygenases (COX) but stabilizes membranes, resulting in local anesthesia; inhibits the production of pro-inflammatory cytokines; inhibits the generation of reactive oxygen species by neutrophils; inhibits leukocyte aggregation and adhesion; and exhibits antimicrobial properties. (NCI04) ( NCI )] (UMLS (NCI) C0282070) =Organic Chemical; Pharmacologic Substance ;
| - 756. Beta Chemokine Exodus-1
- [Repressed by IL-10 and induced by LPS, PMA, TNF, and INF Gamma in liver, lymph nodes, appendix, PBL, thymus, prostate, testis, small intestine, colon, and fetal lung, the human CCL20 Gene product (Intercrine Beta Family), Small Inducible Cytokine A20, is a secreted chemotactic factor for lymphocytes, neutrophils, and dendritic cells that binds CCR6 and may inhibit proliferation of myeloid progenitors. (NCI) ( NCI )] (UMLS (NCI) C1308247) CC Chemokine LARC;
CCL20;
Chemokine (C-C Motif) Ligand 20;
Exodus-1;
Liver and Activation-Regulated Chemokine;
Macrophage Inflammatory Protein 3 Alpha;
MIP-3-Alpha;
Small Inducible Cytokine A20;
Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20 =Amino Acid, Peptide, or Protein; Immunologic Factor |
- 707. BENZYL BENZOATE
- (UMLS (NCI) C0053289) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =benzoate;
Pediculicide;
Inactive Ingredient Preparations;
=BENZYL BENZOATE 1.2 %;
BENZYL BENZOATE 12 MG/GM;
BENZYL BENZOATE 50 %;
| - 757. Beta Chemokine Exodus-3
- [Expressed in lymph nodes, thymus, appendix, colon, trachea, spleen, small intestine, lung, kidney, and stomach by human CCL19 Gene (Intercrine Beta Family), secreted immunoregulatory 98-aa 11-kD (precursor) Small Inducible Cytokine A19 is involved in inflammatory and immunological responses, binds to CCR7 receptor, and plays a role in thymic T cell trafficking and T and B cell migration. (NCI) ( NCI )] (UMLS (NCI) C0539791) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 708. benzylamine
- [toluenes in which one hydrogen of the methyl group is substituted by an amino group. ( CSP )] (UMLS (CSP) C0005106) =Organic Chemical ;
| - 758. Beta Chemokine Receptor-Like 1
- [Up-regulated by chronic inflammation and encoded by human CX3CR1 Gene (CCR Family, Rhodopsin Family), 355-amino acid 40.4-kD high-affinity Fractalkine Receptor is a seven transmembrane protein expressed in brain, peripheral blood leukocytes, and spleen as a regulator of leukocyte endothelial trafficking: chemotaxis, cell migration, and adhesion. CX3CR1 signals through a pertussis toxin sensitive G-protein to induce migration and contains common GPCR features. Tyrosine sulfation enhances fractalkine-induced cell adhesion. Sharing the CX3C motif, RSV G glycoprotein can use CX3CR1 as a receptor. CX3CR1 may be an HIV envelope protein co-receptor with CD4. Homozygous CX3CR1 I249/M280 haplotype enhances infection and progression to AIDS. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1143767) Chemokine (C-C) Receptor-Like 1;
Chemokine (C-X3-C Motif) Receptor 1;
Chemokine, CX3C Motif, Receptor 1;
CMKBLR1;
CMK-BRL-1;
CX3C Chemokine Receptor 1;
C-X3-C CKR-1;
CX3CR1;
CX3CR1 Protein;
Fractalkine Receptor;
Fractalkine Receptor CX3CR1;
G Protein-Coupled Receptor 13;
G Protein-Coupled Receptor V28;
G-Protein Coupled Receptor Family 1 =Amino Acid, Peptide, or Protein; Receptor ;
|
- 709. Bepadin
- (UMLS (NCI) C0206026) =Organic Chemical; Pharmacologic Substance
| - 759. beta counter
- [ ] (UMLS (CSP) C0599391) =Medical Device ;
|
- 710. Berbaman, 6, 6',7,12-trtramethoxy-2,2'-dimethyl-, (1.beta.)-(PM)-(9CI)
- [A natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant Radix stephania tetrandrae. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the cell cycle and apoptosis in various cell types, resulting in immunosuppressive, anti-proliferative and free radical scavenging effects. This agent also increases glucose utilization by enhancing hepatocyte glycogen synthesis, resulting in the lowering of plasma glucose. (NCI04) ( NCI )] (UMLS (NCI) C0076316) =Organic Chemical; Pharmacologic Substance ;
| - 760. Beta DNA polymerase
- [Human DNA polymerase beta protein (334 aa 38 kDa) is encoded by the human DNA polymerase beta (POLB) gene. This monomer protein is a DNA repair enzyme that catalyzes "gap-filling" DNA synthesis in a stepwise, distributive manner during base excision repair. This enzyme is required for DNA maintenance, replication, recombination, and drug resistance. ( NCI )] (UMLS (NCI) C0525039) =Amino Acid, Peptide, or Protein; Enzyme
|
- 711. berbine alkaloid
- [ ] (UMLS (CSP) C0053338) =Organic Chemical; Pharmacologic Substance ;
| - 761. Beta Endorphin
- [A neuropeptide that mediates pain perception. ( NCI )] (UMLS (NCI) C0005210) =Amino Acid, Peptide, or Protein; Neuroreactive Substance or Biogenic Amine ;
|
- 712. bereavement
- [process of grieving and mourning; associated with a deep sense of loss and sadness. ( CSP )] (UMLS (CSP) C0005119) =Mental Process ;
| - 762. beta fructofuranosidase
- [A glycoside hydrolase found primarily in PLANTS and YEASTS. It has specificity for beta-D-fructofuranosides such as SUCROSE. ( MSH )] (UMLS (CSP) C0053409) =Amino Acid, Peptide, or Protein; Enzyme ;
=O glycosidase;
|
- 713. BEREAVEMENT, UNCOMPLICAT
- (UMLS (ICD9CM) C0684255) =Finding ;
| - 763. beta galactocerebrosidase deficiency
- [inherited, demyelinating, human lipid storage disease caused by a deficiency of galactosylceramidase; manifestations include convulsions, quadriplegia, blindness, deafness, and mental retardation. ( CSP )] (UMLS (CSP) C0023521) =Disease or Syndrome ;
=LEUKODYSTROPHY;
Sphingolipidoses;
inborn lysosomal enzyme disorder;
enzyme deficiency;
Hereditary Central Nervous System Demyelinating Diseases;
|
- 714. Bergers disease
- [most common cause of primary glomerular disease in Europe, Australia, and United States; lesions formed as a consequence of mesangial formations of immune deposits composed of IgA. ( CSP )] (UMLS (CSP) C0017661) =Disease or Syndrome ;
=autoimmune disease;
glomerulonephritis | - 764. beta galactosidase
- [A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1. ( MSH )] (UMLS (CSP) C0005220) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Enzyme
|
- 715. Beri Beri
- [A disease caused by a deficiency of thiamine (vitamin B1) and characterized by polyneuritis, cardiac pathology, and edema. The epidemic form is found primarily in areas in which white (polished) rice is the staple food, as in Japan, China, the Philippines, India, and other countries of southeast Asia. (Dorland, 27th ed) ( MSH )] (UMLS (NCI) C0005122) =Disease or Syndrome ;
| - 765. beta galactosidase deficiency
- [form of gangliosidosis characterized by accumulation of G(M1) ganglioside and oligosaccharides in lysosomes caused by an absence or severe deficiency of the enzyme beta-galactosidase (type A1); three phenotypes of this disorder are infantile (generalized), juvenile, and adult; the infantile form is characterized by skeletal abnormalities, hypotonia, poor psychomotor development, hirsutism, hepatosplenomegaly, and facial abnormalities; the juvenile form features hyperacusis, seizures, and psychomotor retardation; the adult form features progressive intellectual deterioration, involuntary movements, ataxia, and spasticity. ( CSP )] (UMLS (CSP) C0085131) =Disease or Syndrome ;
=Gangliosidoses;
enzyme deficiency |
- 716. Beriplast P
- (UMLS (NCI) C0879437) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 766. beta globin
- [ ] (UMLS (CSP) C0005221) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 717. Berna Products
- (UMLS (HL7) C1546865) =Manufactured Object =Manufacturers of Vaccines (code=MVX);
| - 767. beta globulin
- [group of serum proteins with an electrophoretic mobility that falls between alpha globulins and gamma globulins. ( CSP )] (UMLS (CSP) C0005157) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 718. Berna Products Corporation
- (UMLS (HL7) C1546866) =Health Care Related Organization =Manufacturers of Vaccines (code=MVX);
| - 768. beta glucosidase
- [An exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of GLUCOSE. ( MSH )] (UMLS (CSP) C0005223) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 719. Berna Products Corporation (includes Swiss Serum and Vaccine Institute Berne)
- [Berna Products Corporation (includes Swiss Serum and Vaccine Institute Berne) ( HL7V3.0 )] (UMLS (HL7) C1552887) =Health Care Related Organization =VaccineManufacturer;
| - 769. beta glucuronidase
- [ ] (UMLS (CSP) C0017776) =Amino Acid, Peptide, or Protein; Enzyme; Indicator, Reagent, or Diagnostic Aid =O glycosidase;
|
- 720. Berna Products [Inactive - use BPC]
- [Berna Products [Inactive-use BPC] ( HL7V3.0 )] (UMLS (HL7) C1552886) =Health Care Related Organization =VaccineManufacturer;
| - 770. beta heparin
- [naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue, differs from chondroitin sulfate A by containing iduronic acid in place of glucuronic acid, its epimer, at carbon atom 5. ( CSP )] (UMLS (CSP) C0011602) =Carbohydrate; Biologically Active Substance =chondroitin;
chondroitin sulfate =danaparoid;
|
- 721. Bernard Horner syndrome
- [syndrome associated with defective sympathetic innervation to one side of the face, including the eye; clinical features include miosis, mild blepharoptosis, and hemifacial anhidrosis (decreased sweating); lesions of the brain stem, cervical spinal cord, first thoracic nerve root, apex of the lung, carotid artery, cavernous sinus, and apex of the orbit may cause this condition. ( CSP )] (UMLS (CSP) C0019937) =Disease or Syndrome =Disorder of eye, unspecified;
Miosis;
syndrome;
autonomic disorder | - 771. beta hydroxybutyrate
- [butyric acid substituted in the beta or 3 position; one of the ketone bodies produced in the liver and occurs at high levels in the blood and urine in ketosis. ( CSP )] (UMLS (CSP) C0106006) =Organic Chemical; Biologically Active Substance =butyrate;
|
- 722. Bernard Soulier syndrome
- [A familial coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, and impaired prothrombin consumption. ( MSH )] (UMLS (CSP) C0005129) =Disease or Syndrome ;
| - 772. beta hydroxybutyrate dehydrogenase
- [ ] (UMLS (CSP) C0020331) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 723. Bernese Mountain Dog
- [The Bernese Mountain Dog is a sturdy, heavy dog, with a weather-resistant, tri-color double coat. The dog has a white blaze on the chest, white on the head and toes, and rust markings over each eye, on the cheeks, sides of the chest, under the tail and on each leg. The broad head has a slight furrow down the middle. The medium-sized triangular ears are pendant. Height: 23-28 inches (58-71 cm.) Weight: 80-110 pounds (36-50 kg.) ( NCI )] (UMLS (NCI) C0324313) =Mammal
| - 773. Beta IGH3
- [Constitutively expressed by human TGFBI Gene in many tissues (high in corneal epithelium) and TGF-beta induced, highly conserved 683-aa 75-kDa (precursor) extracellular Transforming Growth Factor-Beta Induced Protein IGH3 contains an N-signal peptide, four 140-aa FAS1 domains with internal homology, and a C-RGD motif. RGD is found in many extracellular matrix proteins that modulate cell adhesion and serves as a ligand recognition sequence for several integrins. With similar structure to fasciclin I (putative neuronal cell adhesion protein) and OSF-2 (potential bone adhesion protein), TGFBI binds to types I, II, and IV collagens. A potential adhesion protein, TGFBI may play role in cell-collagen interactions, may be associated with microfibrils and the cell surface, and may be involved in endochondral bone formation. TGFBI defects cause CDGG1, CDRB, CDL1, CDL3A, and ACD. (NCI) ( NCI )] (UMLS (NCI) C0172642) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 724. Berrimah virus
- [ ] (UMLS (CSP) C0599349) =Virus ;
| - 774. Beta Interferon
- [major interferon produced by double stranded RNA induced fibroblast cultures; the primary producer cells are fibroblasts, epithelial cells and macrophages, and the major activity is antiviral. ( CSP )] (UMLS (NCI) C0015980) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =Interferon Type I;
IFN =interferon beta 1b;
interferon beta 1a;
|
- 725. berry aneurysm
- [ ] (UMLS (CSP) C0005136) =Disease or Syndrome; Anatomical Abnormality
| - 775. Beta Interferon
- [A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. (NCI05) ( NCI )] (UMLS (NCI) C0751599) Human Interferon Beta;
Interferon Beta;
Interferon, Beta;
Interferon-B;
Interferon-beta;
Recombinant Interferon Beta;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance |
- 726. Berry Creek Rancheria of Maidu Indians of Californ
- (UMLS (HL7) C1554233) =Population Group =NativeEntityContiguous;
| - 776. beta lactam antibiotic
- [group of antibiotics containing beta lactam rings which are cleaved by the beta lactamases produced by almost all gram negative bacteria. ( CSP )] (UMLS (CSP) C0026458) =Organic Chemical; Antibiotic =Antibiotics;
lactam =[AM100] CEPHALOSPORINS;
[AM050] PENICILLINS;
|
- 727. berylliosis
- [lung disease caused by exposure to metallic beryllium or its soluble salts. ( CSP )] (UMLS (CSP) C0005138) =Disease or Syndrome
| - 777. beta lactam hydrolase
- [enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring well known antibiotics destroyed by these enzymes are penicillins and cephalosporins. ( CSP )] (UMLS (CSP) C0597979) =Amino Acid, Peptide, or Protein; Enzyme =amidinohydrolase;
|
- 728. Beryllium Chloride
- [A yellowish, crystalline, inorganic compound with a sharp odor that emits toxic fumes of beryllium oxides, hydrochloric acid and other chlorinated compounds upon heating. Beryllium chloride is mainly used to produce beryllium metal, but is also used as an acid catalyst in organic reactions. Inhalation exposure to its dust irritates the nose, throat and lungs and can cause pneumonitis. Prolonged exposure can result in a chronic beryllium disease called berylliosis causing granuloma and fibrosis formation in the lungs. Beryllium is a known human carcinogen and is associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0053345) =Inorganic Chemical
| - 778. beta lactoglobulin
- [ ] (UMLS (CSP) C0005248) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 729. Beryllium Compound
- [An inorganic substance that contains the metallic element beryllium with excellent thermal and electrical conductivity and is corrosion resistant. Beryllium compounds are used in the electronics, automotive, aerospace, defense and nuclear industries. Inhalation exposure to beryllium compounds can cause pneumonitis, and prolonged exposure can result in berylliosis, characterized by occurrence of granulomatous fibrosis in the lungs. Beryllium compounds are known human carcinogens and are associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0303131) =Inorganic Chemical
| - 779. beta lipotropin
- [A 90-amino acid peptide derived from post-translational processing of pro-opiomelanocortin (POMC) in the PITUITARY and the HYPOTHALAMUS. It is the C-terminal fragment of POMC with lipid-mobilizing activities, such as LIPOLYSIS and steroidogenesis. Depending on the species and the tissue sites, beta-LPH may be further processed to yield active peptides including GAMMA-LIPOTROPIN; BETA-MSH; and ENDORPHINS. ( MSH )] (UMLS (CSP) C0023832) =Amino Acid, Peptide, or Protein; Hormone ;
|
- 730. Beryllium Fluoride
- [A white colored, crystalline, inorganic compound that emits toxic fumes of beryllium oxides, hydrofluoric acid and other fluorinated compounds upon heating. Beryllium fluoride is mainly used to produce beryllium metal and alloys and is also used in the production of glass and nuclear reactors. Inhalation exposure to its dust irritates the nose, throat and lungs and can cause pneumonitis. Prolonged exposure can result in a chronic beryllium disease called berylliosis causing granuloma and fibrosis formation in the lungs. Beryllium is a known carcinogen and is associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0053346) =Inorganic Chemical
| - 780. beta mannosidase
- [An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS. ( MSH )] (UMLS (CSP) C0053413) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 731. Beryllium Hydroxide
- [A white colored, crystalline, inorganic compound that emits toxic fumes of beryllium oxides upon heating. Beryllium hydroxide is mainly used to produce beryllium metal and alloys. Inhalation exposure to its dust irritates the nose, throat and lungs and can cause pneumonitis. Prolonged exposure can result in a chronic beryllium disease called berylliosis causing granuloma and fibrosis formation in the lungs. Beryllium is associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0053347) =Inorganic Chemical
| - 781. beta methylaspartase
- [ ] (UMLS (CSP) C0066329) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 732. Beryllium Oxide
- [A white colored, crystalline, inorganic compound that emits toxic fumes of beryllium oxides upon heating. Beryllium oxide is widely used in industry due to its low density and high thermal and electrical conductivity. It is used in high-technology ceramics, electronic heat sinks, electrical insulators, high-power devices, high-density electrical circuits, microwaves, X-ray windows, nuclear reactor fuels and for various aerospace and military applications. Inhalation exposure to its dust irritates the nose, throat and lungs and can cause pneumonitis. Prolonged exposure can result in a chronic beryllium disease called berylliosis causing granuloma and fibrosis formation in the lungs. Beryllium is associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0053349) =Inorganic Chemical
| - 782. beta N acetylglucosaminidase
- [A beta-N-Acetylhexosaminidase that catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as MUCOLIPIDOSIS and various inflammatory disorders of muscle and connective tissue. ( MSH )] (UMLS (CSP) C0001057) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 733. Beryllium Sulfate
- [A white colored, crystalline, inorganic compound that emits toxic fumes of beryllium oxides and sulfur oxides upon heating. Beryllium sulfate is mainly used to produce beryllium oxide for high-technology ceramics. Inhalation exposure to its dust and fumes irritates the nose, throat and lungs and can cause pneumonitis. Prolonged exposure can result in a chronic beryllium disease called berylliosis causing granuloma and fibrosis formation in the lungs. Beryllium is associated with an increased risk of developing lung cancer. (NCI05) ( NCI )] (UMLS (NCI) C0053351) =Indicator, Reagent, or Diagnostic Aid; Inorganic Chemical ;
| - 783. beta N acetylhexosaminidase
- [A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease. ( MSH )] (UMLS (CSP) C0005270) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 734. Besnier Boeck disease
- [inflammatory disease characterized by small lumps or granulomas in lymph nodes and other organs. ( CSP )] (UMLS (CSP) C0036202) =Disease or Syndrome ;
=Lymphoproliferative Disorder;
immunopathology =Lung Sarcoidosis;
Uveoparotid Fever | - 784. Beta Particle
- [radioactive decay particles consisting of an electron (e-) ejected at high speed; the main emission of tritium, 14-carbon, 32-phosphorus, and other isotopes used in biochemistry. ( CSP )] (UMLS (NCI) C0005166) =Natural Phenomenon or Process
|
- 735. BESpm
- [A synthetic bis-ethyl analogue of spermine with potential antineoplastic activity. N(1),N(11)-bis(ethyl)norspermine (DENSPM), a N-terminally alkylated tetraamine and polyamine mimetic, disrupts polyamine pool homeostasis by modulating the activities of the biosynthetic enzymes, ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (AdoMetDC). This agent also reduces polyamine concentrations through the induction of the catabolic enzyme spermidine/spermine N1-acetyltransferase 1 (SSAT). Polyamines, an integral part of the DNA helix structure, play a critical role in cell division, differentiation and membrane function. Disruption of normal polyamine concentrations by DENSPM may lead to cell growth inhibition. ( NCI )] (UMLS (NCI) C0067116) =Organic Chemical; Pharmacologic Substance ;
| - 785. Beta Platelet-Derived Growth Factor Receptor
- [Platelet-Derived Growth Factor Receptor, Beta Polypeptide, encoded by the PDGFRB gene, is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia. (from LocusLink) ( NCI )] (UMLS (NCI) C0290068) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
|
- 736. beta
- [The beta-distribution is used for data that is bounded on both sides and may or may not be skewed (e.g., occurs when probabilities are estimated.) Two parameters a and b are available to adjust the curve. The mean m and variance s2 relate as follows: m = a/ (a + b) and s2 = ab/((a + b)2 (a + b + 1)). ( HL7V3.0 )] (UMLS (HL7) C1552649) =Qualitative Concept =ProbabilityDistributionType;
| - 786. beta pleated sheet
- [In a b-sheet two or more polypeptide chains run alongside each other and are linked in a regular manner by hydrogen bonds between the main chain C=O and N-H groups. The R-groups (side chains) of neighbouring residues in a b-strand point in opposite directions; beta sheets can be parallel, anti-parallel or mixed. (from expasy.org) ( NCI )] (UMLS (CSP) C0599215) =Cell Component
|
- 737. Beta 2 Integrin Chain
- [Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGB2 encodes the integrin beta 2 chain. Mutations in the beta-2 subunit of the leukocyte cell adhesion molecule have been found to cause the autosomal recessive disorder of neutrophil function known as leukocyte adhesion deficiency(from LocusLink) ( NCI )] (UMLS (NCI) C0064830) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 787. beta secretase
- [ ] (UMLS (CSP) C1454853) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 738. beta 2 microglobulin
- [An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants. ( MSH )] (UMLS (CSP) C0005149) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
| - 788. Beta Subunit, Signal-Transducing Proteins GS/GI
- [Encoded by human GNB1 Gene, Guanine Nucleotide Binding Protein Beta 1 is a heterotrimeric G protein beta subunit that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. (NCI) ( NCI )] (UMLS (NCI) C1333884) G Protein, Beta-1 Subunit;
GNB1;
Guanine Nucleotide Binding Protein Beta 1;
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 1;
Guanine Nucleotide-Binding Protein, Beta-1 Subunit;
Transducin Beta Chain 1 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 739. beta adrenergic agent
- [drug that selectively binds to and activates beta adrenergic receptors. ( CSP )] (UMLS (CSP) C0178503) =Pharmacologic Substance ;
=adrenergic agent;
| - 789. Beta TG
- [Encoded by human PPBP Gene (Alpha Chemokine CXC Family), secreted 128-aa 14-kDa (precursor) Pro-Platelet Basic Protein is a platelet-derived growth factor that is processed to PBP and CTAP-III. Upon platelet activation, PBP is proteolytically converted to Beta Thromboglobulin, a homotetramer released when platelets aggregate. Proteolytic removal of PPBP residues 1-9 produces active peptide CTAP-III/LA-PF4, which stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan, as well as formation and secretion of plasminogen activator. CTAP-III is also proteolytically converted to NAP2, a potent chemoattractant and activator of neutrophils. (NCI) ( NCI )] (UMLS (NCI) C0005286) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 740. beta adrenergic receptor
- [coupled through the G protein Gs to adenylate cyclase such that extracellular stimulation results in increased intracellular cyclic AMP; beta-1 mediates lipolysis and cardiostimulation, beta-2 broncho- and vaso- dilation. ( CSP )] (UMLS (CSP) C0034785) =Amino Acid, Peptide, or Protein; Receptor ;
=adrenergic receptor;
| - 790. Beta Thalassemia
- [A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. ( MSH )] (UMLS (NCI) C0005283) =Disease or Syndrome
|
- 741. Beta Adrenergic Receptor Gene
- [Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptor Genes encode Beta Adrenergic Receptors, one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI) ( NCI )] (UMLS (NCI) C1332546) =Gene or Genome
| - 791. beta thalassemia major anemia
- [ ] (UMLS (CSP) C0599528) =Disease or Syndrome ;
|
- 742. beta adrenergic receptor kinase
- [G-protein-coupled receptor kinases that mediate agonist-dependent PHOSPHORYLATION and desensitization of BETA-ADRENERGIC RECEPTORS. ( MSH )] (UMLS (CSP) C0053379) =Amino Acid, Peptide, or Protein; Enzyme; Receptor =alcohol phosphotransferase;
| - 792. beta thionase
- [A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22. ( MSH )] (UMLS (CSP) C0010641) =Amino Acid, Peptide, or Protein; Enzyme =dehydratase;
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- 743. beta alanine
- [An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. ( MSH )] (UMLS (CSP) C0000392) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
| - 793. beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide
- [A sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter. ( NCI )] (UMLS (NCI) C0114771) =Organic Chemical; Pharmacologic Substance =[CV300] ANTIARRHYTHMICS;
Phenethylamines;
sulfonamide;
=dofetilide 0.125 MG;
dofetilide 0.25 MG;
dofetilide 0.5 MG |
- 744. beta alanine receptor
- [ ] (UMLS (CSP) C0598529) =Amino Acid, Peptide, or Protein; Receptor
| - 794. beta-(p-Hydroxyphenyl)isopropylamine Hydrobromide
- [The hydrobromide salt form of hydroxyamphetamine, an indirect-acting sympathomimetic amine with adrenergic properties. Hydroxyamphetamine, when applied topically to the eye, stimulates the release of norepinephrine from postganglionic adrenergic nerves resulting in the stimulation of both alpha and beta adrenergic receptors. Local alpha stimulatory effects include dilation of the pupil, increased flow of aqueous humor and vasoconstriction; whereas, beta stimulatory effects include relaxation of the cilary muscle and a decreased production in aqueous humor. ( NCI )] (UMLS (NCI) C0282278) =Organic Chemical; Pharmacologic Substance =HYDROXYAMPHETAMINE;
=HYDROXYAMPHETAMINE HYDROBROMIDE 1 % |
- 745. beta aminopropionitrile
- [3-aminopropanenitrile; reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid. ( CSP )] (UMLS (CSP) C0085885) =Organic Chemical; Hazardous or Poisonous Substance =Mutagen;
alkyl nitrile | - 795. Beta-Alanine Metabolism
- [The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] ( GO )] (UMLS (NCI) C1156837) Beta-Alanine Metabolism Pathway;
=Molecular Function |
- 746. beta amylase
- [An enzyme that catalyzes the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains. EC 3.2.1.2. ( MSH )] (UMLS (CSP) C0005194) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 796. beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, Sulfamate
- [A sulfamate-substituted monosaccharide with anticonvulsant property. Although the mechanism of action has not been fully elucidated, topiramate antagonizes kainate/AMPA subtype of the glutamate receptors, which are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. This antagonistic action results in stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing propagation of synaptic impulses, thereby impedes seizure occurrences. In addition, this agent augments gamma-aminobenzoic acid (GABA) activity and thereby attenuating GABAnergic inhibitory transmission. ( NCI )] (UMLS (NCI) C0076829) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
fructose =TOPIRAMATE 15 MG;
TOPIRAMATE 200 MG;
TOPIRAMATE 25 MG;
TOPIRAMATE 100 MG;
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- 747. beta antiadrenergic agent
- [drug that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists; adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. ( CSP )] (UMLS (CSP) C0178504) =Pharmacologic Substance ;
=adrenergic antagonist;
=atenolol;
ENALAPRIL;
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol;
| - 797. beta-D-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-, 3-acetate 1-(decahydro-5''-methyl-''-((1-oxo-3-phenyl-2-propenyl)oxy)dispiro(oxirane-2,3'(2'H)-benzofuran-2',2''-(2H)pyran)-6'
- (UMLS (NCI) C0070989) =Organic Chemical ;
|
- 748. beta barrel
- [ ] (UMLS (CSP) C0599216) =Amino Acid Sequence
| - 798. Beta-D-Glucosyl-Ifosfamide Mustard
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0912322) glc-IPM;
GLUFOSFAMIDE =Organophosphorus Compound; Biologically Active Substance |
- 749. beta carotene/VIT-A
- (UMLS (NCI) C0281420) =Therapeutic or Preventive Procedure
| - 799. Beta-Glucan
- [A type of polysaccharide (string of sugar molecules) obtained from several types of mushrooms. It is being studied as a treatment for cancer and as an immune system stimulant. ( NCI )] (UMLS (NCI) C1134651) =Carbohydrate; Pharmacologic Substance ;
|
- 750. Beta Catenin
- [Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete. (from OMIM) ( NCI )] (UMLS (NCI) C0105770) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 800. Beta-Glucan/Monoclonal Antibody 3F8
- (UMLS (NCI) C1134652) =Therapeutic or Preventive Procedure
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