- 1. Ap3A Hydrolase
- [FHIT protein is a 147-amino acid AP3A hydrolase. The FHIT preferred substrate, AP3A (diadenosine 5-prime,5-triple prime-P(1),P(3)-triphosphate), and AP4A have been proposed to have various intracellular functions, including regulation of DNA replication and signaling stress responses. (from OMIM) ( NCI )] (UMLS (NCI) C1173495) AP3Aase;
bis(5'-adenosyl)-triphosphatase;
Diadenosine 5',5'''-P1,P3-triphosphate Hydrolase;
Dinucleosidetriphosphatase;
FHIT;
FHIT Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 6. APAF1
- [This gene is involved in pro-apoptotic regulation through caspase interaction. ( NCI )] (UMLS (NCI) C1332098) APAF1 Gene;
Apoptotic Protease Activating Factor 1 Gene =Gene or Genome ;
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- 2. Apache
- (UMLS (NCI) C0337855) =Population Group =American Indian;
=Chiricahua;
Fort Sill Apache;
Jicarilla Apache;
Lipan Apache;
Mescalero Apache;
Oklahoma Apache;
Payson Apache;
San Carlos Apache;
White Mountain Apache | - 7. APAF3
- [Caspase-9 is encoded by the CASP9 Gene. Caspase-9 is the most upstream member of the apoptotic protease cascade that is triggered by cytochrome c and dATP. Caspase-9 and APAF1 bind to each other in the presence of cytochrome c and dATP, an event that leads to caspase-9 activation. Activation of procaspase-9 by APAF1 requires proteolytic cleavage to generate the mature caspase molecule. Activated caspase-9 in turn cleaves and activates caspase-3. APAF1-mediated processing of procaspase-9 occurs at asp315 by an intrinsic autocatalytic activity of procaspase-9 itself. APAF1 can form oligomers and may facilitate procaspase-9 autoactivation by oligomerizing its precursor molecules. Once activated, caspase-9 can initiate a biochemical cascade involving the downstream executioners caspase-3, -6, and -7. Alternative splicing of this gene results in two transcript variants which encode different isoforms. (From LocusLink, OMIM and NCI) ( NCI )] (UMLS (NCI) C0910167) APAF-3;
Apoptotic Protease Activating Factor 3;
Apoptotic Protease MCH-6;
CASP9;
CASP-9;
CASP9 Protein;
Caspase 9, Apoptosis-Related Cysteine Protease;
Caspase-9;
EC 3.4.22.-;
ICE-LAP6;
ICE-Like Apoptotic Protease 6;
MCH6 =Amino Acid, Peptide, or Protein; Enzyme |
- 3. Apache Tribe of Oklahoma
- (UMLS (HL7) C1554225) =Population Group =NativeEntityContiguous;
| - 8. Apartment
- [A room or suite of rooms designed as a residence and generally located in a building occupied by more than one household used as an element of an address. ( NCI )] (UMLS (NCI) C0457933) =Manufactured Object
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- 4. Apachean
- (UMLS (HL7) C1698047) =Language ;
=Athapaskan;
=Kiowa Apache;
EasternApachean;
WesternApachean;
| - 9. apatite
- [family of minerals composed of mutilples of Ca5-(PO4)6-OH; one of the 2 major minerals of bones and teeth, the other being calcium carbonate. ( CSP )] (UMLS (CSP) C0003522) =Inorganic Chemical ;
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- 5. APAF1
- [The APF1 protein functions to activate caspase 9 in the cytochrome c/dATP-dependent apoptotic pathway. (from RefSeq Summary) ( NCI )] (UMLS (NCI) C0664613) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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