- 8701. cytologic technique
- [study of cells; their origin, structure, function, behavior, growth and pathology; use this term when emphasis is on a cytologic technique; for other studies see CELL BIOLOGY. ( CSP )] (UMLS (CSP) C1305671) cytology =Laboratory Procedure =Histology;
=cell separation;
Cytogenetic;
Cell/Tissue, Histochemistry;
cell population study;
laser capture microdissection;
subcellular fractionation | - 8729. Cytoskeletal Gene
- [Cytoskeletal Genes encode Cytoskeletal Proteins, diverse structural proteins including polymerizable globular subunits (actin, tubulin), "motor ATPases" (myosin, dynein), membrane-supporting linkers (spectrin, clathrin), fibrous proteins (keratin, vimentin), and many more. As constituents of the cytoskeleton, Cytoskeletal Proteins form a flexible cellular framework that provides attachment points for organelles and formed bodies and makes communication between cell parts possible. (NCI) ( NCI )] (UMLS (NCI) C1333200) =Gene or Genome ;
|
- 8702. Cytologic Technique
- [Technique for manipulation of cells and analysis of cell properties and subcellular features. ( NCI )] (UMLS (NCI) C0010818) =Laboratory Procedure ;
| - 8730. cytoskeletal protein
- [diverse family of structural proteins, including polymerizable globular subunits (actin, tubulin), "motor ATPases" (myosin, dynein), membrane-supporting linkers (spectrin, clathrin), fibrous proteins (keratin, vimentin), and many more. ( CSP )] (UMLS (CSP) C0010852) =Amino Acid, Peptide, or Protein; Biologically Active Substance =gene product;
=ABP;
actin;
clathrin;
keratin;
MAP;
spectrin;
tubulin;
vimentin;
ankyrin;
neurofilament protein;
protein 4.1;
myocilin |
- 8703. Cytology
- [The light microscopic study of normal and abnormal cells in fine needle aspirates (FNAs), body cavity fluids, and smears. — 2004 ( NCI )] (UMLS (NCI) C0010819) =Biomedical Occupation or Discipline ;
| - 8731. cytosol
- [The aqueous part of the cytoplasm within which various particles and organelles are suspended. ( NCI )] (UMLS (CSP) C0010854) =Cell Component ;
|
- 8704. Cytology and Pathology
- [A branch of pathology that studies and diagnoses diseases on the cellular level including the anatomy, physiology, pathology and chemistry of the cell. ( NCI )] (UMLS (NCI) C0243139) =Occupation or Discipline ;
| - 8732. Cytosolic Protein Tyrosine Phosphastase
- [dephosphorylates O phosphotyrosine groups in phosphoproteins. ( CSP )] (UMLS (NCI) C0085536) =Amino Acid, Peptide, or Protein; Enzyme =phosphatase;
|
- 8705. cytolysin
- [group of substances elaborated by microorganisms, plants or animals that are specifically toxic to individual cells; they may be involved in immunity or may be contained in venoms. ( CSP )] (UMLS (CSP) C0010821) =Hazardous or Poisonous Substance ;
=Toxin;
=hemolysin;
| - 8733. Cytosolic Protein Tyrosine Phosphatase Gene
- [Non-Receptor Protein Tyrosine Phosphatase Genes encode Non-Receptor Protein Tyrosine Phosphatases, one of the two main categories (soluble and transmembrane receptor) of enzymes that catalyze removal of a tyrosine-attached phosphate group and are important in control of cell growth, proliferation, differentiation, and transformation. Two cysteines in the catalytic domain (one absolutely required for activity) are generally conserved; other conserved residues in the vicinity are important. (NCI) ( NCI )] (UMLS (NCI) C1335055) Non-Receptor Protein Tyrosine Phosphatase Gene;
=Gene or Genome ;
|
- 8706. cytolysis
- [pathologic dissolution or disintegration of cells. ( CSP )] (UMLS (CSP) C1536403) =Cell Function; ;
=Cytotoxicity;
=Autolysis;
bacteriolysis;
Hemolysis;
| - 8734. cytosolic receptor
- [ ] (UMLS (CSP) C0872141) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 8707. CYTOMEGALOVIRAL DISEASE
- [Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults. ( MSH )] (UMLS (ICD9CM) C0010823) =Disease or Syndrome ;
=Herpesviridae disease;
=CMV retinitis;
| - 8735. cytospectrophotometry
- [ ] (UMLS (CSP) C0598877) =Research Activity ;
|
- 8708. Cytomegaloviral Pneumonia
- (UMLS (NCI) C0276253) =Disease or Syndrome
| - 8736. Cytostasan
- (UMLS (NCI) C0057000) =Organic Chemical; Pharmacologic Substance ;
|
- 8709. Cytomel
- (UMLS (NCI) C0010826) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 8737. Cytotacin
- [novel glioma-mesenchymal extracellular matrix glycoprotein; promotes cell attachment. ( CSP )] (UMLS (NCI) C0076088) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Adhesion Molecule;
Extracellular Matrix Protein |
- 8710. Cytometry
- [The measurement of physical and /or chemical characteristics of cells, or, by extension, of other biological particles. ( NCI )] (UMLS (NCI) C0814048) =Laboratory Procedure
| - 8738. Cytotec
- (UMLS (NCI) C0591321) =Eicosanoid; Pharmacologic Substance ;
|
- 8711. Cytopathology
- (UMLS (HL7) C1547979) =Intellectual Product =Diagnostic Service Section ID;
| - 8739. Cytotechnology
- (UMLS (HL7) C1552390) =Intellectual Product =Specialist/Technologist, Pathology;
|
- 8712. Cytopathology
- [A cytopathologist is an anatomic pathologist trained in the diagnosis of human disease by means of the study of cells obtained from body secretions and fluids, by scraping, washing, or sponging the surface of a lesion, or by the aspiration of a tumor mass or body organ with a fine needle. A major aspect of a cytopathologist's practice is the interpretation of Papanicolaou-stained smears of cells from the female reproductive systems, the "Pap" test. However, the cytopathologist's expertise is applied to the diagnosis of cells from all systems and areas of the body. He/she is a consultant to all medical specialists. A subspecialty certificate was first issued by the ABMS in 1989.ACGME Accredited Residency Program Requirements: None. ( HL7V3.0 )] (UMLS (HL7) C1555817) =Professional or Occupational Group =pathologist;
| - 8740. Cytotoxic
- [Anticancer drugs that kill cells, especially cancer cells. ( NCI )] (UMLS (NCI) C0677881) =Therapeutic or Preventive Procedure ;
|
- 8713. cytopenia
- [A reduction in the number of blood cells. ( NCI )] (UMLS (CSP) C0010828) =Pathologic Function ;
| - 8741. Cytotoxic Lymphocyte Maturation Factor 2, p40
- [This protein is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggested the role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. (LocusLink) ( NCI )] (UMLS (NCI) C1099914) IL12B;
IL23, subunit p40;
Interkeukin-12 beta chain;
Interleukin 12, p40;
Interleukin 12B;
Interleukin-12B;
Natural Killer Cell Stimulatory Factor-2 =Amino Acid, Peptide, or Protein; Immunologic Factor |
- 8714. cytoplasm
- [protoplasm of a cell exclusive of that of the nucleus; it consists of a continuous aqueous solution (cytosol) and the organelles and inclusions suspended in it (phaneroplasm), and is the site of most of the chemical activities of the cell. ( CSP )] (UMLS (CSP) C0010834) =Cell Component ;
=cell component;
=20S Catalytic Proteasome;
caveola | - 8742. cytotoxic lymphocyte reaction
- [ ] (UMLS (CSP) C0598093) =Cell or Molecular Dysfunction ;
|
- 8715. Cytoplasmic Inclusion
- [Cell substance ( UWDA )] (UMLS (NCI) C0205708) =Cell Component
| - 8743. Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 Gene
- [This gene is involved in the regulation of osteoclastogenesis and plays a role in rheumatoid arthritis. ( NCI )] (UMLS (NCI) C1334108) IL17;
IL17 Gene;
=Gene or Genome |
- 8716. Cytoplasmic Organelle
- [Cell part which consists of macromolecules aggregated into discrete structures in the protoplasm. (Digital Anatomist Foundational Model) ( NCI )] (UMLS (NCI) C1179962) =Cell Component ;
| - 8744. Cytotoxic TRAIL Receptor
- [Receptor for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) ( NCI )] (UMLS (NCI) C1504635) Death Receptor 4;
TNF-Related Apoptosis Inducing Ligand Receptor 1;
TNFRSF10A;
TRAIL Receptor 1;
Tumor Necrosis Factor Receptor Superfamily, Member 10A;
=Amino Acid, Peptide, or Protein; Receptor ;
|
- 8717. Cytoplasmic Protein
- [Protein within the interior of the cell; excludes membrane, mitochondrial, and nuclear proteins. ( NCI )] (UMLS (NCI) C1333198) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 8745. Cytotoxicity
- [Bioassay, Cytotoxicity ( HL7V3.0 )] (UMLS (HL7) C1551412) =Laboratory Procedure =ObservationMethod;
|
- 8718. Cytoplasmic Protein Gene
- [Cytoplasmic Protein Genes encode Cytoplasmic Proteins that are typically localized in the cell interior, generally excluding the plasma membrane, mitochondria, and the nucleus. (NCI) ( NCI )] (UMLS (NCI) C1333199) =Gene or Genome ;
| - 8746. Cytotoxicity
- [relating to or producing a toxic effect on cells. ( CSP )] (UMLS (NCI) C0596402) =Cell or Molecular Dysfunction ;
=Cellular Biology;
=autophagy;
cell death;
cytoprotection;
cytolysis |
- 8719. Cytoplasmic Protein NCK2
- [Encoded by human NCK2 Gene, ubiquitous 380-aa 43-kDa cytoplasmic NCK Adaptor Protein 2, containing 1 SH2 domain and 3 SH3 domains, associates with tyrosine-phosphorylated growth factor receptors or their substrates. NCK2 interacts with PINCH and DOCK1. NCK2 shares 68% amino acid identity with NCK-alpha; most differences occur outside the SH2/SH3 domains. NCK2 associates with PDGF and EGF receptors via p62DOK and inhibits DNA synthesis. NCK2 binds to B ephrin cytoplasmic domains in a phosphotyrosine-dependent manner. NCK2-dependent (SH2 domain) B ephrin signaling increases FAK activity, redistributes paxillin, inhibits focal adhesions, and disassembles F-actin fibers. NCK2 SH3 domains bind proteins implicated in cytoskeletal regulation: CAP/ponsin, ABI1, dynamin, PAK1, HNRNPK, and axin. (NCI) ( NCI )] (UMLS (NCI) C1334865) GRB4;
NCK Adaptor Protein 2;
NCK-2;
NCKBeta;
SH2/SH3 Adaptor Protein NCK-Beta =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 8747. cytotoxicity test
- [ ] (UMLS (CSP) C0201622) =Laboratory Procedure
|
- 8720. Cytoplasmic Receptor
- [proteins in the cytoplasm or nucleus that specifically bind signaling molecules and trigger changes which influence the behavior of cells; major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus; not all cytoplasmic receptors are tree'd under this term. ( CSP )] (UMLS (NCI) C0206587) =Amino Acid, Peptide, or Protein; Receptor =Receptor;
=antigen receptor;
complement receptor;
cytokine receptor | - 8748. Cytotrophoblast
- [Trophoblasts with single nucleus and defined cellular structures. As the PLACENTA develops, pockets of cytotrophoblasts serve as stem cells for syncytiotrophoblasts. ( MSH )] (UMLS (NCI) C0230960) =Embryonic Structure
|
- 8721. Cytoprotectants
- [Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the normal cells. (NCI) ( NCI )] (UMLS (NCI) C1268903) Cytoprotective Agent;
Cytoprotective Drugs;
=Pharmacologic Substance; ;
| - 8749. Cytovene
- (UMLS (NCI) C0701307) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 8722. cytoprotection
- [protection of a cell against harm or harmful agents by chemicals or biologicals. ( CSP )] (UMLS (CSP) C0524828) =Physiologic Function ;
=Cytotoxicity;
| - 8750. CZ
- [A country in Central Europe, southeast of Germany. (NCI) ( NCI )] (UMLS (NCI) C0206578) =Geographic Area =Europe;
|
- 8723. Cytosar
- (UMLS (NCI) C0591320) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 8751. [1-[[[(2-chloroethyl)nitrosamino]-carbonyl]amino]ethyl]phosphonic acid diethyl ester
- [A chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier. ( NCI )] (UMLS (NCI) C0060696) =Organic Chemical; Pharmacologic Substance ;
|
- 8724. cytosine analog
- [synthetic or natural chemical compounds which resemble cytosine in structure and/or function. ( CSP )] (UMLS (CSP) C0596400) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =pyrimidine analog;
=5 methylcytosine;
1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine | - 8752.
- [minute protoplasmic masses that make up organized tissue, consisting of a nucleus which is surrounded by protoplasm which contains the various organelles and is enclosed in the cell or plasma membrane; cells are the fundamental, structural, and functional units of living organisms. ( CSP )] (UMLS (NCI) C0007634) =Cell =Normal Tissue;
=ameloblast;
accessory cell;
blood cell;
chromatophore;
Connective and Soft Tissue Cell;
eukaryote;
gamete;
Granulosa Cell;
Keratinocyte;
Interstitial cell of Leydig;
glia;
nerve cell;
Sertoli Cell;
spore;
Mother cell;
protoplast/spheroplast;
hepatocyte;
gangliocyte;
Chromaffin Cell;
cell type;
Goblet Cell;
kidney cell;
acinar cell;
basal cell;
brain cell;
fiber cell;
Muscle Cell;
neoplastic cell;
prokaryote;
heart cell;
embryo/fetus cell/tissue |
- 8725. cytosine deaminase
- [An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE. ( MSH )] (UMLS (CSP) C0056997) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 8753. /L
- [A unit of cell concentration expressed as a number of cells in unit volume equal to one liter. ( NCI )] (UMLS (NCI) C0347983) =Quantitative Concept
|
- 8726. cytosine nucleoside
- [condensation product of a cystosine base plus a sugar. ( CSP )] (UMLS (CSP) C0596401) =Nucleic Acid, Nucleoside, or Nucleotide ;
=pyrimidine nucleoside;
=.beta.-Cytosine arabinoside;
cytidine;
deoxycytidine;
| - 8754. /uL
- [A unit of cell concentration expressed as a number of cells in unit volume equal to one microliter. ( NCI )] (UMLS (NCI) C0439378) =Quantitative Concept
|
- 8727. cytosine nucleotide
- [one of the monomeric units from which DNA or RNA polymers are constructed, consisting of a cytosine base, a pentose sugar, and a phosphate group. ( CSP )] (UMLS (CSP) C0010848) =Nucleic Acid, Nucleoside, or Nucleotide ;
=pyrimidine nucleotide;
| - 8755.
- [Passage through time; duration; a systematic or/and orderly succession; a sequence, e.g. course of treatment; a mode of action or behavior; natural development, typical manner of proceeding. ( NCI )] (UMLS (NCI) C0750729) Course =Temporal Concept ;
|
- 8728. Cytoskeletal Filament
- (UMLS (NCI) C0010851) =Cell Component ;
| |
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