CD CD1 CD2 CD3 CD4 CD5 CD6 CD7 CD8 CD9 CDA CDB CDC CDD CDE CDG CDH CDI CDK CDL CDM CDN CDO CDP CDR CDS CDT CDV CDW
CDC2L1
[Cell Division Cycle 2-Like 1, encoded by the CDC2L1 gene, is a member of the p34Cdc2 serine/threonine protein kinase family. CDC2L1 is expressed ubiquitously and acts as a negative regulator of the normal cell cycle progression. It may function in regulating proliferation by phosphorylation and subsequent plasma membrane targeting of galactosyltransferase. This gene is deleted or altered frequently in neuroblastoma with amplified MYCN genes. CDC2L1 can be cleaved by caspases and play roles in cell apoptosis. A large number of the alternatively spliced variants of this gene exist. (From LocusLink, Swiss-Prot and NCI) ( NCI )]
UMLS (NCI) C0138869- Amino Acid, Peptide, or Protein
- Enzyme
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