CAIN
[Expressed in thymus, spleen, bone marrow, kidney, brain, and testis by human NUP214 Gene (FG-Repeat NUP Family), 2090-aa 214-kDa homodimeric Nuclear Pore Complex Protein NUP214, likely glycosylated, contains F-G repeats and is associated with cytoplasmic filaments and the cytoplasmic face of the nuclear pore complex. NUP214 is required for proper cell cycle progression and, as a nuclear pore component, may regulate nucleocytoplasmic transport by serving as a docking site in receptor-mediated nuclear import. NUP214 interacts with DDX19 and NUP88. Involved in some cases of leukemia, chromosomal translocation t(6;9)(p23;q34) results in a DEK-NUP214 fusion gene, while chromosomal translocation t(6;9)(q21;q34.1) involves a NUP214/SET gene fusion. (NCI) ( NCI )]
UMLS (NCI) C1366674CAN
CAN Protein
N214
Nuclear Pore Complex Protein NUP214
Nucleoporin 214kDa
Nucleoporin NUP214
NUP214
p250
CAN Protein
N214
Nuclear Pore Complex Protein NUP214
Nucleoporin 214kDa
Nucleoporin NUP214
NUP214
p250
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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