Carbamic Acid,(3-((2-methoxy-4-((((2-methylphenyl)sulfonyl)amino)carbonyl)phenyl)methyl)-1-methyl-1H-indol-5-yl)-, Cyclopentyl Ester
[A toyl compound with anti-asthmatic property. Zafirlukast selectively and competitively binds and blocks the cysteinyl leukotriene 1 receptor , thereby preventing potent proinflammatory mediators leukotriene C4, D4 and E4 from binding. This prevents leukotriene-mediated actions, including enhanced migration of eosinophils and neutrophils, increased adhesion of leukocytes, increased monocyte and neutrophil aggregation, increased airway edema, inflammation, capillary permeability and bronchoconstriction. ( NCI )]
UMLS (NCI) C0378466- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Tosyl Compounds
[RE108] ANTIASTHMA, ANTILEUKOTRIENES
[RE108] ANTIASTHMA, ANTILEUKOTRIENES
Relation/CHD: ZAFIRLUKAST 20 MG
ZAFIRLUKAST 10 MG
ZAFIRLUKAST 10 MG
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