IPO-B

[Encoded by human SOD2 Gene (Fe/Mn SOD Family), 222-aa 25-kDa (precursor) Manganese Superoxide Dismutase is a homotetrameric free radical scavenging indophenoloxidase in the mitochondrial matrix that is required for normal cell function. A first line of defense against toxic superoxide radical byproducts of the energy generating oxidative phosphorylation pathway, MnSOD maintains the integrity of mitochondrial respiratory chain enzymes susceptible to inactivation by superoxide. Reactive oxygen species and oxidative stress are implicated in a range of degenerative processes including ALS, ischemic heart disease, Alzheimer disease, Parkinson disease, and aging. Mitochondria are the chief source of reactive oxygen species in the cell. (NCI) ( NCI )]

UMLS (NCI) C0968147

Manangese Superoxide Dismutase
Manganese Superoxide Dismutase
Mitochondrial Superoxide Dismutase
Mitochondrial Superoxide Dismutase 2
Mn Superoxide Dismutase
MNSOD
Superoxide Dismutase 2

Amino Acid, Peptide, or Protein
Enzyme

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