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Integrin Beta-5
[Human integrin beta-5 protein (799 aa, ~88 kD) is encoded by the integrin, beta 5 gene (ITGB5). This type I membrane protein forms a heterodimer with integrin alpha-V protein. The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration. ( NCI )]
UMLS (NCI) C0249042- Amino Acid, Peptide, or Protein
- Receptor
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