- 1101. GLI1
- [This gene plays a regulatory role in transcription and embryonic development. ( NCI )] (UMLS (NCI) C0812304) GLI1 Gene;
Glioma-Associated Oncogene Homolog 1 (Zinc Finger Protein) Gene =Gene or Genome | - 1151. glomerular filtration rate
- [rate at which plasma is filtered by the glomerular filtration membrane into Bowman's space; determined by the permeabiliy of the membrane, hydrostatic pressure in the glomerular capillaries and Bowman's space, and the colloid osmotic pressure exerted by the proteins of the capillary plasma. ( CSP )] (UMLS (CSP) C0017654) =Organ or Tissue Function; Diagnostic Procedure =glomerular filtration;
|
- 1102. GLI2
- [A Kruppel family protein, GLI2 Protein contains five DNA-binding zinc finger repeats and is implicated in transduction of the SHH signal. GLI2 is a putative oncogene in the development of human BCC. The expression of GLI2 in skin results in activation of multiple SHH target genes. (from OMIM 165230 and NCI) ( NCI )] (UMLS (NCI) C0218975) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 1152. glomerular sclerosis
- [fibrosis and scarring of the renal glomeruli involving a part of or the entire glomerulus; can be limited to a small area or can be diffused throughout the entire kidney; caused by diabetic nephropathy, chronic glomerular nephritis, nephrotic syndrome, or renal hypertension. ( CSP )] (UMLS (CSP) C0178664) =Disease or Syndrome ;
=Kidney Disease;
|
- 1103. GLI2
- [This gene is involved in transcriptional regulation and plays a role in sonic hedgehog signal transduction. ( NCI )] (UMLS (NCI) C0812306) GLI2 Gene;
GLI-Kruppel Family Member GLI2 Gene =Gene or Genome | - 1153. Glomerular Vascular Disorder
- (UMLS (NCI) C0852683) =Disease or Syndrome
|
- 1104. GLI3
- [GLI3 Protein is a putative zinc finger DNA-binding transcription factor of the GLI-Kruppel family. GLI3 is homologous to Drosophila Cubitus interruptus (Ci), which regulates patched, gooseberry, and decapentaplegic genes. In response to hedgehog signaling, the full-length cytoplasmic transcriptional activator form of Ci can be cleaved to a nuclear transcription repressor form. Based on GLI3 mutations and phenotypes, GLI3 shows transcriptional activation or repression, and subcellular localization, similar to Ci. Cytoplasmic GLI3 activates PTCH gene expression. PKA-dependent processing of vertebrate GLI3 in the developing limb generates the repressor form, which appears to be antagonized by sonic hedgehog signaling. Mutations of GLI3 may be responsible for Greig Cephalopolysyndactyly Syndrome, Pallister-Hall Syndrome, and Postaxial Polydactyly, suggesting specific roles during development. (from OMIM 165240 and NCI) ( NCI )] (UMLS (NCI) C0082708) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 1154. glomerular visceral epithelial cell
- [cells of the visceral epithelium that closely invest the network of glomerular capillaries in the kidney. ( CSP )] (UMLS (CSP) C1328818) Podocyte;
Visceral Epithelial Cell;
visceral glomerular epithelial cell =Cell ;
=Glomerular;
kidney cell |
- 1105. GLI3
- [This gene plays a regulatory role in limb development and is involved in sonic hedgehog signal transduction. ( NCI )] (UMLS (NCI) C0812382) GLI3 Gene;
GLI-Kruppel Family Member GLI3 (Greig Cephalopolysyndactyly Syndrome) Gene =Gene or Genome ;
| - 1155. Glomeruloid Hemangioma
- (UMLS (NCI) C1304511) =Disease or Syndrome
|
- 1106. glia
- [non-neuronal cells of the nervous system; they provide physical support, respond to injury, regulate the ionic and chemical composition of the extracellular milieu, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. ( CSP )] (UMLS (CSP) C0027836) =Cell ;
= ;
Body System, Neurologic =astrocyte;
oligodendrocyte;
Neurilemmal Cell;
gitter cell;
Muller's cell;
| - 1156. glomerulonephritis
- [glomerular disease characterized by an inflammatory reaction, with leukocyte infiltration and cellular proliferation of the glomeruli, or that appears to be the result of immune glomerular injury. ( CSP )] (UMLS (CSP) C0017658) =Disease or Syndrome ;
=autoimmune disease;
nephritis =Bergers disease;
Glomerulonephritis, Membranous;
Lupus Glomerulonephritis;
Anti-Glomerular Basement Membrane Disease;
Bergers disease;
Glomerulonephritis, Membranoproliferative;
Glomerulonephritis, Membranous;
FGS (focal glomerular sclerosis);
Lupus Glomerulonephritis;
Anti-Glomerular Basement Membrane Disease;
|
- 1107. Gliadel Wafer
- (UMLS (NCI) C1171407) =Clinical Drug ;
| - 1157. Glomerulonephritis/nephrosis
- (UMLS (ICPC) C0497424) (Glomerulonephritis/nephrosis; GLOMERULONEFRITIA/NEFROSIA; Glumerulonefrit/nefrose; Glomerulonephritis/nefrose; GLOMERULONEFRIITTI/NEFROOSI; Glomerulonephrite/syndr nephr; Glomerulonephritis/Nephrot Syndrom; glomerulonefritis/nefrozis; glomerulonephritis/nephrosis; Glomerulonefrite/nefrosi; GLOMERULONEFRITT/NEFROSE - n00 - n01 - n03 - n04 - n05 - n07 -; Glomerulonefrite/nefrose; Glomerulonefritis/nefrosis; GLOMERULONEFRIT/NEFROS) =Disease or Syndrome =Urologic; Diagnosis/Diseases Component
|
- 1108. glial cell tumor
- [new abnormal neuroglial tissue in any one of its stages of development that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease. ( CSP )] (UMLS (CSP) C0017638) =Neoplastic Process =Neoplasm of Nervous System;
Neoplasm of Neuroepithelial Tissue =astrocytic glioma;
ependymoma;
Medulloblastoma;
astrocytic glioma;
ependymoma;
Medulloblastoma;
Oligodendroglioma;
ganglioglioma;
Glioblastoma with a Sarcomatous Component | - 1158. Glomus Cell
- (UMLS (NCI) C0229571) =Cell
|
- 1109. Glial Neoplasm Spinal Cord
- [Benign and malignant neoplasms that arise from glial cells of the spinal cord. Subtypes include ependymoma, astrocytoma (including low and high grade forms), medulloblastoma, and oligodendroglioma. ( NCI )] (UMLS (NCI) C0346294) =Neoplastic Process
| - 1159. Glomus Jugulare Neoplasm
- [A benign or malignant extra-adrenal parasympathetic paraganglioma arising from paraganglia in the base of the skull and middle ear. ( NCI )] (UMLS (NCI) C0017671) =Neoplastic Process ;
=Extraadrenal Paraganglioma;
|
- 1110. Glibenclamide
- [N-4-beta-(2-methoxy-5-chlorobenzamido) -ethylbenzosulfonyl-N'- cyclohexylurea; hypoglycemic used against non-insulin dependent diabetes mellitus; thought to act by increasing insulin receptor expression in target tissues. ( CSP )] (UMLS (NCI) C0017628) =Organic Chemical; Pharmacologic Substance ;
=sulfonylurea;
[HS502] HYPOGLYCEMIC AGENTS, ORAL =GLYBURIDE 1.25 MG;
GLYBURIDE 1.5 MG;
GLYBURIDE 2.5 MG;
GLYBURIDE 3 MG;
GLYBURIDE 5 MG;
GLYBURIDE 6 MG;
GLYBURIDE 4.5 MG | - 1160. Glomus Neoplasm
- [A rare benign or malignant mesenchymal neoplasm arising from cells that resemble the modified smooth muscle cells of the glomus body. The majority of glomus tumors occur in the distal extremities. ( NCI )] (UMLS (NCI) C0017653) =Neoplastic Process =Extraadrenal Paraganglioma;
blood vessel neoplasm |
- 1111. gliding bacteria
- [ ] (UMLS (CSP) C0017633) =Bacterium
| - 1161. Glomus Neoplasm of Skin
- [A glomus tumor arising from the skin. It usually presents as a small red-blue nodule and it often associated with pain at the site. ( NCI )] (UMLS (NCI) C0346083) =Neoplastic Process
|
- 1112. GLIMEPIRIDE
- [A sulfonylurea with antihyperglycemic activity. Glimepiride binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, thereby reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-gated calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin, and thereby results in a reduction of the blood glucose level. In addition, this agent increases the sensitivity of peripheral tissues to insulin. ( NCI )] (UMLS (NCI) C0061323) =Organic Chemical; Pharmacologic Substance ;
=sulfonylurea;
[HS502] HYPOGLYCEMIC AGENTS, ORAL =GLIMEPIRIDE 1 MG;
GLIMEPIRIDE 4 MG;
GLIMEPIRIDE 2 MG;
| - 1162. Glomus Tumor of Uncertain Malignant Potential
- [A glomus tumor that shows atypical characteristics and has borderline malignant potential. ( NCI )] (UMLS (NCI) C1333826) =Neoplastic Process ;
|
- 1113. Glioblastoma with a Sarcomatous Component
- [A type of glioma (cancer of the brain that comes from glial, or supportive, cells). ( NCI )] (UMLS (NCI) C0206726) =Neoplastic Process =glial cell tumor;
| - 1163. Glossaries
- [Glossary; an alphabetical list of technical terms in some specialized field of knowledge; usually published as an appendix to a text on that field. ( NCI )] (UMLS (NCI) C0681470) =Intellectual Product ;
|
- 1114. Gliofibroma
- [An astrocytic tumor affecting young people. Morphologically, it is characterized by the presence of collagenous tissue surrounding neoplastic astrocytes. In some cases the collagen is produced by the tumor cells (desmoplastic astrocytoma), whereas in others it is produced by mesenchymal cells (mixed glioma/fibroma). ( NCI )] (UMLS (NCI) C1266178) =Neoplastic Process
| - 1164. glossary
- [Refers to a document providing a glossary of terms that pertain to the current document. ( HL7V3.0 )] (UMLS (HL7) C1552855) =Idea or Concept =HtmlLinkType;
|
- 1115. Glioma of Optic Nerve
- [Abnormal growth of cells that comprise the optic tract. This condition can be seen in association with Neurofibromatosis 1. It is most commonly seen in the pediatric age group. ( NCI )] (UMLS (NCI) C0346326) =Neoplastic Process =astrocytic glioma;
Cranial Nerve II Neoplasms | - 1165. Glossina
- [ ] (UMLS (CSP) C1011177) =Invertebrate
|
- 1116. Glioma of Optic Tract
- [A rare, slow-growing tumor of the eye. ( NCI )] (UMLS (NCI) C0796418) Glioma of the Optic Tract;
Glioma of the Visual Pathway;
Glioma of Visual Pathway;
Optic Tract Glioma;
visual pathway glioma =Neoplastic Process | - 1166. Glossinidae
- [family of Diptera occurring only in Africa. ( CSP )] (UMLS (CSP) C0242639) =Invertebrate ;
=Diptera;
|
- 1117. Glioma Tumor Suppressor Candidate Region Gene 1 Gene
- [This gene may play a role in the negative regulation of cell growth. ( NCI )] (UMLS (NCI) C1333679) GLTSCR1;
GLTSCR1 Gene;
=Gene or Genome ;
| - 1167. GLOSSITIS
- [Inflammation of the tongue. ( MSH )] (UMLS (ICD9CM) C0017675) =Disease or Syndrome ;
=Tongue Diseases;
=GEOGRAPHIC TONGUE |
- 1118. Glioma Tumor Suppressor Candidate Region Gene 1 Protein
- [Glioma Tumor Suppressor Candidate Region Gene 1 Protein is encoded by the human GLTSCR1 gene. This protein is expressed at moderate levels in heart, brain, placenta, skeletal muscle, and pancreas, and at lower levels in lung, liver, and kidney. Mutation analysis of the transcripts in the gene region in diffuse gliomas with 19q deletions revealed no tumor-specific mutations. However, a marker in GLTSCR1, presumably separated from RAI by several million bases, supplements the most significant marker in RAI in separating cases of basal cell carcinoma (BCC) from controls, which may suggest the presence of an independent, risk-modulating variation in this second gene region. (From OMIM, Swiss-Prot, PubMed 12117772 and NCI) ( NCI )] (UMLS (NCI) C1333680) GLTSCR1;
GLTSCR1 Protein;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 1168. GLOSSOPHAR NERVE DIS NEC
- [ ] (UMLS (ICD9CM) C0393797) =Disease or Syndrome
|
- 1119. Glioma Tumor Suppressor Candidate Region Gene 2 Gene
- [This gene plays a role in the regulation of protein phosphorylation and turnover. ( NCI )] (UMLS (NCI) C1333682) GLTSCR2;
GLTSCR2 Gene;
=Gene or Genome ;
| - 1169. GLOSSOPHARYNG NEURALGIA
- [ ] (UMLS (ICD9CM) C0154731) =Disease or Syndrome
|
- 1120. Glioma Tumor Suppressor Candidate Region Gene 2 Protein
- [Expressed in heart, pancreas, placenta, liver, skeletal muscle, kidney, brain, and lung by human GLTSCR2 Gene (GLTSCR2 Family), 478-aa 54-kDa nuclear Glioma Tumor Suppressor Candidate Region Gene 2 Protein interacts with HSV-1 early proteins ICP22 and ICP0. GLTSCR2 function is unknown. (NCI) ( NCI )] (UMLS (NCI) C1333681) GLTSCR2;
GLTSCR2 Protein;
p60 =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 1170. Glossopharyngeal Motor Neuropathy
- (UMLS (NCI) C0751942) =Disease or Syndrome ;
|
- 1121. Gliomatosis of Meninges
- (UMLS (NCI) C1334695) Gliomatosis of the Meninges;
Meningeal Gliomatosis;
Meninges Gliomatosis;
=Neoplastic Process | - 1171. Glossopharyngeal Nerve Neoplasm
- (UMLS (NCI) C1263900) Glossopharyngeal Nerve Neoplasms;
Glossopharyngeal Nerve Tumor;
Glossopharyngeal Nerve Tumors;
IXth Cranial Nerve Neoplasms;
IXth Cranial Nerve Tumors;
Neoplasm of Glossopharyngeal Nerve;
Neoplasm of Ninth Cranial Nerve;
Neoplasm of the Glossopharyngeal Nerve;
Neoplasm of the Ninth Cranial Nerve;
Ninth Cranial Nerve Neoplasm;
Ninth Cranial Nerve Neoplasms;
Ninth Cranial Nerve Tumor;
Ninth Cranial Nerve Tumors;
Tumor of Glossopharyngeal Nerve;
Tumor of Ninth Cranial Nerve;
Tumor of the Glossopharyngeal Nerve;
Tumor of the Ninth Cranial Nerve;
=Neoplastic Process |
- 1122. gliosis
- [an excess of neuroglia in damaged areas of the central nervous system. ( CSP )] (UMLS (CSP) C0017639) =Pathologic Function =Central Nervous System Disease;
Pathologic Process | - 1172. Glossopharyngeal Nerve Paralysis
- (UMLS (NCI) C0919940) =Disease or Syndrome
|
- 1123. GLIPIZIDE
- [1-cyclohexyl-3-(p-(2-(5-methyl pyrazinecarboxamido) ethyl) phenyl) sulfonylurea; a typical member of the sulfonylurea family of type II (NIDDM) antidiabetic drugs. ( CSP )] (UMLS (NCI) C0017642) =Organic Chemical; Pharmacologic Substance ;
=sulfonylurea;
[HS502] HYPOGLYCEMIC AGENTS, ORAL =GLIPIZIDE 5 MG;
GLIPIZIDE 10 MG;
GLIPIZIDE 2.5 MG | - 1173. Glottic Verrucous Carcinoma
- (UMLS (NCI) C0280329) =Neoplastic Process
|
- 1124. Glisson's Sphincter
- [The muscle fibres around the opening of the common bile duct (ductus choledochus) into the duodenum at the papilla of Vater. ( NCI )] (UMLS (NCI) C0028872) =Body Part, Organ, or Organ Component
| - 1174. Glottis
- [(GLAH-tis) The middle part of the larynx; the area where the vocal cords are located. ( NCI )] (UMLS (NCI) C0017681) =Body Part, Organ, or Organ Component ;
|
- 1125. GLMN
- (UMLS (NCI) C1333678) GLMN Gene;
Glomulin, FKBP Associated Protein Gene;
=Gene or Genome ;
| - 1175. Glottis Neoplasm
- (UMLS (NCI) C0345713) =Neoplastic Process
|
- 1126. Gln
- [non-essential amino acid present abundantly throughout the body and involved in many metabolic processes; synthesized from glutamic acid and ammonia; the principal carrier of nitrogen in the body and an important energy source for many cells. ( CSP )] (UMLS (NCI) C0017797) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=primary aminoacid;
| - 1176. GLP
- [Islands in the eastern Caribbean Sea, southeast of Puerto Rico. (NCI) ( NCI )] (UMLS (NCI) C0018301) =Geographic Area ;
|
- 1127. global introspection
- [Reaching a decision by consideration of the totality of factors involved in order to reach a judgement. ( HL7V3.0 )] (UMLS (HL7) C1553906) =Health Care Activity =DecisionObservationMethod;
| - 1177. GLUC
- [Glucose Plasma Concentration (GPC) measurement is an essential diagnostic modality for different types of carbohydrate metabolism derangements including diabetes mellitus. The disordered carbohydrate metabolism that underlies diabetes manifests as hyperglycemia. Plasma glucose concentrations in healthy individuals vary with age. Normal fasting plasma glucose intervals (in the morning after an overnight fast) in children are 3.3 - 5.6 mmol/L (60-100 mg/dL); adult range - 4.1- 5.9 mmol/L (74-106 mg/dL). GPCs are approximately 11% higher than whole blood if the hematocrit is normal. Glucose concentrations in heparinized plasma are reported to be 5% lower than in serum. ( NCI )] (UMLS (NCI) C0202042) =Laboratory Procedure
|
- 1128. globin
- [protein constituent of hemoglobin; also used for any member of a group of proteins similar to the typical globin; do not confuse with GLOBULIN. ( CSP )] (UMLS (CSP) C0017645) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=gene product;
=haptoglobin;
hemoglobin;
myoglobin | - 1178. glucagon like peptide
- [ ] (UMLS (CSP) C0598680) =Amino Acid, Peptide, or Protein ;
|
- 1129. Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH Conjugate Vaccine
- [A multivalent vaccine comprised epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32-mer, TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens. ( NCI )] (UMLS (NCI) C0935834) =Organic Chemical; Pharmacologic Substance; Immunologic Factor
| - 1179. glucan
- [group of polysaccharides composed of repeating glucose units; they can consist of branched or unbranched chains in any linkages. ( CSP )] (UMLS (CSP) C0017696) =Carbohydrate =glycan;
hexosan =cellulose;
cyclodextrin;
glycogen;
starch;
DEXTRAN;
cellulose;
Dextrans;
maltose;
starch |
- 1130. Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH Conjugate Vaccine/QS21
- [A multivalent vaccine comprised of Globo H (Globo H Hexasaccharide 1), GM2, Lewis-y, MUC1-32-mer, TF(c), and Tn(c) antigens conjugated with Keyhole Limpet Hemocyanin, an immunomodulator, plus QS21, an immune enhancer. (NCI) ( NCI )] (UMLS (NCI) C0935835) =Therapeutic or Preventive Procedure
| - 1180. glucocerebrosidase
- [A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45. ( MSH )] (UMLS (CSP) C0017768) =Amino Acid, Peptide, or Protein; Enzyme ;
=Glycosylceramidase;
O glycosidase =alglucerase;
Imiglucerase |
- 1131. Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine
- [A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens. (NCI04) ( NCI )] (UMLS (NCI) C1134578) =Organic Chemical; Pharmacologic Substance; Immunologic Factor
| - 1181. Glucocorticoid deficiency
- [ ] (UMLS (ICD9CM) C1955741) GLUCOCORTICOID DEFICIENT;
=Disease or Syndrome |
- 1132. Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine/QS21
- [A heptavalent vaccine comprised of Globo-H (Globo H Hexasaccharide 1), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) antigens conjugated with Keyhole Limpet Hemocyanin, an immunomodulator, plus QS21, an immune enhancer. (NCI) ( NCI )] (UMLS (NCI) C1134579) =Therapeutic or Preventive Procedure
| - 1182. glucocorticoid receptor
- [Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example. ( MSH )] (UMLS (CSP) C0034809) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 1133. globose nucleus
- [ ] (UMLS (CSP) C0175489) =Body Part, Organ, or Organ Component
| - 1183. Glucocorticoid Receptor
- [Widely expressed by human NR3C1 Gene (NR3 Family) as 6 isoforms, phosphorylated cytoplasmic (inactive)/hyperphosphorylated nuclear (active) Glucocorticoid Receptor contains a (N) modulating domain, a DNA-binding domain, and a (C) steroid-binding domain. Alpha-A (777-aa, 86-kDa precursor) predominates. Complexed with HSP90, HSP70, and FKBP5 or PPP5C, activate GR is transported (by dynein/FKBP4) to the nucleus and binds to target GREs as a homodimeric or heterodimeric (NR3C2/RXR) transcription factor and modulates other transcription factors to regulate blood glucose concentration, protein/fat metabolism, inflammatory responses, cell proliferation, and differentiation. GR appears to interact with NRIP1, POU2F1, POU2F2, STAT5A, STAT5B, SMARCA4, CREBBP/EP300, TADA2L, p160, NCOA2, and NCOA6. Sumoylation and BAG1 interaction inhibits transactivation. GR defects cause glucocorticoid resistance. (NCI) ( NCI )] (UMLS (NCI) C1370369) Glucocorticoid Receptor, Lymphocyte;
NR3C1;
Nuclear Receptor Subfamily 3, Group C, Member 1 =Amino Acid, Peptide, or Protein; Receptor |
- 1134. globoside
- [Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease. ( MSH )] (UMLS (CSP) C0017647) =Lipid; Biologically Active Substance ;
| - 1184. Glucocorticoid Receptor-Interacting Protein-1
- [Involved in cell growth, development, and homeostasis, 292-kb human NCOA2 Gene at 8q13.2 encodes 1464-aa 159-kD transcriptional coactivator TIF2, containing N-terminal bHLH and PAS dimerization domains. Present in a complex with NCOA3, IKKA/B, IKBKG, and CREBBP histone acetyltransferase, TIF2 interacts with HIF1A, APEX, NR3C1, and perhaps NR3C2. TIF2 coactivator interacts with steroid receptor superfamily hormone binding domains in a hormone-dependent manner. Recruitment of CBP/p300 and PCAF coactivators for myogenic MYOD and MEF2 expression depends on NCOA1, NCOA2, and NCOA3. NCOA2 is also required for expression of MYOG and CDKN1A, and for myogenic differentiation. The NCOA2 bHLH/PAS and C-terminal activation domains mediate coactivation of MEF2C through its MADS box. The NCOA2 N- and C-termini interact with MYOG. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1411929) NCOA2;
NCoA-2;
Nuclear Receptor Coactivator 2;
Nuclear Receptor Coactivator-2;
TIF2;
TIF2/GRIP-1;
Transcriptional Intermediary Factor 2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 1135. Globoside Metabolism
- [The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] ( GO )] (UMLS (NCI) C1158414) Globoside Metabolism Pathway =Molecular Function
| - 1185. Glucocorticoid-remediable aldosteronism
- (UMLS (ICD9CM) C1260386) GLUCRTCOD-REM ALDSTERNSM =Disease or Syndrome
|
- 1136. Globular Hyaline Body
- (UMLS (NCI) C1333823) =Finding ;
| - 1186. glucogenesis
- [ ] (UMLS (CSP) C0598530) =Molecular Function ;
|
- 1137. globular protein
- [structural class of water-soluble, spherical, tightly coiled proteins which display a linear relationship between hydrodynamic radius and molecular weight. ( CSP )] (UMLS (CSP) C0178663) =Amino Acid, Peptide, or Protein ;
=protein structure;
| - 1187. glucokinase
- [A group of enzymes that catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate. They are found in invertebrates and microorganisms, and are highly specific for glucose. (Enzyme Nomenclature, 1992) EC 2.7.1.2. ( MSH )] (UMLS (CSP) C0017713) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
|
- 1138. GLOBULE
- [Also called pellets or pilules, are made of pure sucrose, lactose, or other polysaccharides. They are formed into small globular masses of various sizes, and are medicated by placing them in a vial and adding the liquid drug attenuation in the proportion not less than one percent (v/w). After shaking, the medicated globules are dried at temperatures not to exceed 40 degrees Centigrade. (NCI) ( NCI )] (UMLS (NCI) C1337528) Globule Dosage Form;
Globule Dose Form =Biomedical or Dental Material; ;
| - 1188. gluconate
- [hexonic acid or its salts derived from glucose by oxidation of the aldehyde group at C-1 to a carboxyl group. ( CSP )] (UMLS (CSP) C0017714) =Carbohydrate; Biologically Active Substance ;
=sugar acid;
=Calcium D-gluconate;
COPPER GLUCONATE;
GLUCONATE |
- 1139. globulin
- [do not confuse with GLOBIN. ( CSP )] (UMLS (CSP) C0017649) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=blood protein;
gene product =alpha globulin;
cryoglobulin;
macroglobulin;
serum globulin;
myeloma globulin;
serum globulin;
TG | - 1189. gluconeogenesis
- [biosynthesis of glucose from 3-carbon precursors, including aminoacids (this is the basis of protein breakdown during starvation). ( CSP )] (UMLS (NCI) C0017715) =Molecular Function =carbohydrate biosynthesis;
glucose metabolism |
- 1140. Globus Hystericus
- (UMLS (NCI) C0017650) =Mental or Behavioral Dysfunction
| - 1190. glucophage
- [ ] (UMLS (CSP) C0591573) =Organic Chemical; Pharmacologic Substance ;
|
- 1141. globus pallidus
- [The representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. It forms the smaller, more medial part of the lentiform nucleus. (MeSH) ( NCI )] (UMLS (CSP) C0017651) =Body Part, Organ, or Organ Component
| - 1191. Glucosamine Sulfate
- [An amino sugar (2-amino, 2-deoxyglucose) in cell membranes, Glucosamine Sulfate is believed to play a role in cartilage formation and repair. Long-term glucosamine sulfate treatment retards progression of knee osteoarthritis; the mechanism appears to involve glucosamine's role as an essential substrate for glycosaminoglycans and hyaluronic acid, needed for formation of the joint proteoglycan structural matrix. (NCI04) ( NCI )] (UMLS (NCI) C0017720) =Carbohydrate; Pharmacologic Substance ;
|
- 1142. GLOBUS PALLIDUS OPS
- [ ] (UMLS (ICD9CM) C0195781) =Therapeutic or Preventive Procedure
| - 1192. glucose 1 phosphatase
- [ ] (UMLS (CSP) C0061413) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1143. glomangioma
- [A morphologic variant of the glomus tumor characterized by the presence of dilated veins, surrounded by small clusters of glomus cells. Glomangiomas are most often present in patients with multiple lesions. ( NCI )] (UMLS (CSP) C0334421) =Neoplastic Process
| - 1193. glucose 1 phosphate
- [ ] (UMLS (CSP) C0061414) =Carbohydrate; Biologically Active Substance ;
|
- 1144. Glomangiomatosis
- [A benign multifocal proliferation of glomus cells forming clusters around dilated vascular spaces. ( NCI )] (UMLS (NCI) C1333824) =Neoplastic Process ;
| - 1194. glucose 6 phosphatase
- [An enzyme that catalyzes the conversion of D-glucose 6-phosphate and water to D-glucose and orthophosphate. EC 3.1.3.9. ( MSH )] (UMLS (CSP) C0017755) =Amino Acid, Peptide, or Protein; Enzyme ;
=phosphatase;
|
- 1145. Glomangiomyoma
- [A morphologic variant of the glomus tumor with architectural features similar to solid glomus tumor. It is characterized by the presence of elongated glomus cells which resemble mature smooth muscle. ( NCI )] (UMLS (NCI) C0334422) =Neoplastic Process
| - 1195. glucose 6 phosphate
- [ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells; a normal constituent of resting muscle and probably in constant equilibrium with fructose-6-phosphate. ( CSP )] (UMLS (CSP) C0061418) =Carbohydrate; Biologically Active Substance ;
=glucose phosphate;
|
- 1146. Glomangiosarcoma
- [A very rare morphologic variant of glomus tumor with a size greater than 2 cm. The tumor arises in subfascial or visceral tissues. It characterized by the presence of atypical mitotic figures, or marked nuclear atypia, or the combination of both. It has an aggressive clinical course. ( NCI )] (UMLS (NCI) C1266111) Malignant Glomus Neoplasm;
Malignant Glomus Tumor;
=Neoplastic Process | - 1196. glucose 6 phosphate isomerase
- [An enzyme that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate, and is a part of the glycolytic and gluconeogenic pathways. Deficiency of the enzyme, an autosomal recessive trait, results in liver glycogenesis and hemolytic anemia. EC 5.3.1.9. ( MSH )] (UMLS (CSP) C0017759) =Amino Acid, Peptide, or Protein; Enzyme ;
=isomerase;
|
- 1147. Glomerular
- [globular tufts of capillaries, one projecting into the expanded end or capsule of each the uriniferous tubules. ( CSP )] (UMLS (NCI) C0022663) =Body Part, Organ, or Organ Component =kidney;
=mesangium;
glomerular visceral epithelial cell | - 1197. glucose analog
- [synthetic or natural chemical compounds which resemble naturally occurring glucose in structure and/or function. ( CSP )] (UMLS (CSP) C0596619) =Carbohydrate =analog;
|
- 1148. Glomerular Capillary
- (UMLS (NCI) C0226356) =Body Part, Organ, or Organ Component
| - 1198. glucose clamp technique
- [technique that maintains a constant blood glucose level by perfusion or infusion with glucose or insulin; used in metabolic rate studies. ( CSP )] (UMLS (CSP) C0017728) =Diagnostic Procedure; Research Activity ;
=diagnostic test;
|
- 1149. glomerular endothelium
- [ ] (UMLS (CSP) C0599298) =Body Part, Organ, or Organ Component
| - 1199. glucose dehydrogenase
- [D-Glucose:1-oxidoreductases. Catalyzes the oxidation of D-glucose to D-glucono-gamma-lactone and reduced acceptor. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.47; EC 1.1.1.118; EC 1.1.1.119 and EC 1.1.99.10. ( MSH )] (UMLS (CSP) C0017730) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol oxidoreductase;
|
- 1150. glomerular filtration
- [movement and filtering of the plasma-like glomerular filtrate through the glomerular capillaries into the renal tubules. ( CSP )] (UMLS (CSP) C0232809) =Organ or Tissue Function =kidney function;
=glomerular filtration rate;
| - 1200. Glucose Intolerance
- [A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION. ( MSH )] (UMLS (NCI) C0271650) =Disease or Syndrome =Carbohydrate Metabolism, Inborn Errors;
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